Abstract Negative surgical margins at the time of lumpectomy are essential to achieving optimal patient outcomes. Numerous techniques have been investigated to enhance the accuracy of intraoperative margin analysis. Achieving…
Abstract Breast cancer, like other cancers, is a genetic disease. The disease is caused by acquired molecular alterations during the lifetime of an individual and by inherited mutant genes. Risk…
Abstract Mastectomy complications include infection, lymphedema, pain, deep venous thrombosis, and seroma. The chapter discusses the prevention and management of these complications. Keywords mastectomy, wound infection, lymphedema, seroma, complications …
Abstract The National Institutes of Health (NIH) defines a clinical trial as “a research study in which one or more human subjects are prospectively assigned to one or more interventions…
Abstract Quality measurement is necessary to identify gaps in health care quality and to assess the effectiveness of quality improvement initiatives. Multiple reports measuring the quality of breast cancer care…
Abstract Numerous dermal diseases, including congenital anomalies, benign and malignant neoplasms, and manifestations of various dermatoses, may involve the skin of the breast. These disorders may involve solely the breast…
Abstract Screening and diagnosis for diseases of the breast involve coordination between patients and their multidisciplinary team of physicians. The roles of patients and physicians in the evaluation of breast…
Abstract Management of breast cancer has always been informed by our understanding of the biology of this disease. As we moved from descriptive models to biologically grounded models, we began…
Abstract The concept of the stem cell of origin for cancers was first proposed more than 100 years ago. In this theoretical model, certain cells with self-renewal capacity would form…
Abstract Breast lymphoma and mesenchymal neoplasms of the breast are rare entities. The large continuum of disease includes fibroepithelial, vascular, lipomatous, neural, myogenic, and osseous neoplasms. In this chapter, we…
