Megakaryopoiesis and Thrombopoiesis
SUMMARY Print Section Listen SUMMARY Each day the adult human produces approximately 1 × 1011 platelets, a level of production that can increase 10- to 20-fold in times of increased…
Classification, Clinical Manifestations, and Evaluation of Disorders of Hemostasis
SUMMARY Print Section Listen SUMMARY Evaluation of a hemostatic disorder is commonly initiated when (1) a patient or referring physician suspects a bleeding tendency, (2) a bleeding tendency is discovered…
Reactive Thrombocytosis
SUMMARY Print Section Listen SUMMARY The three major pathophysiologic causes of thrombocytosis are (1) clonal, including essential (or primary) thrombocythemia and other myeloproliferative neoplasms; (2) familial, including rare cases of…
