Mediastinal Tumors
OVERVIEW Print Section Listen The mediastinum is centrally located in the thoracic cavity. It extends from the thoracic inlet to the diaphragm and from the sternum to thoracic spine, and…
Atlas of Trauma: Introduction
INTRODUCTION TO THE ATLAS Print Section Listen Each preceding chapter has figures, tables, and drawings that aid the author and the editors in imparting and clarifying the messages of the…
Nasopharyngeal Cancer
ANATOMY Print Section Listen The nasopharynx is the anatomical region bounded by the sphenoid bone superiorly, the soft palate inferiorly, the clivus and uppermost cervical vertebrae posteriorly, and the nasal…
Pulmonary Metastasectomy
INTRODUCTION Print Section Listen Pulmonary metastasectomy has evolved into a widely accepted and successful treatment strategy for patients with advanced disease of various tumor types. The growth of this surgical…
Lung Cancer: Stage I and II
INTRODUCTION Print Section Listen Lung cancer remains the leading cause of cancer mortality in the United States and worldwide by a large margin. In 2016, there was an estimated 243,820…
Cancer of the Unknown Primary
INTRODUCTION Print Section Listen Carcinoma of unknown primary origin (CUPO) is estimated to represent between 3% and 5% of all head and neck cancer presentations, and can pose a challenge…
Management of Oropharyngeal Squamous Cell Carcinoma
INTRODUCTION Print Section Listen Approximately 41,000 cases of head and neck squamous cell carcinoma (HNSCC) are diagnosed annually in the United States, of which approximately one-third arises within the oropharynx….
Gastrinoma
INTRODUCTION Print Section Listen Gastrinomas are gastrin-secreting neuroendocrine tumors (NETs), usually located in the duodenum or pancreas, that result in hypergastrinemia. This leads to excessive gastric acid secretion and the…
Multiple Endocrine Neoplasia Type 2
BACKGROUND Print Section Listen History The association between thyroid carcinoma and pheochromocytoma (PHEO) was originally reported by Sipple, and in 1968 named as the multiple endocrine neoplasia type 2 syndrome…
Gastrointestinal Neuroendocrine Tumors
BACKGROUND Print Section Listen German pathologist Siegfried Oberndorfer recognized carcinoid tumors as a unique entity in 1907. Prior to his published case reports, these tumors were thought to be benign…
