Updates in Postmastectomy Radiation
Although the use of postmastectomy radiation therapy (PMRT) is widely accepted in certain clinical situations, areas of controversy persist for some clinical scenarios. In addition, with significant shifts in the…
Update on Radiotherapy for Central Nervous System Malignancies
Malignancies arising from the central nervous system are rare. Brain metastases, in contrast, are perhaps the most common neurologic complication of cancer. Radiotherapy, as part of combined modality therapy, continues…
Update of Practical Radiation Oncology Management Trends for Surgeons
Adam Raben, MD, Editor In this latest issue of Surgical Oncology Clinics of North America , updated and emerging trends in the management of selected malignancies with radiation therapy, relevant…
Emerging Updates of Radiation Oncology for Surgeons
SURGICAL ONCOLOGY CLINICS OF NORTH AMERICA www.surgonc.theclinics.com Consulting Editor NICHOLAS J. PETRELLI July 2017 • Volume 26 • Number 3
An Update on Randomized Clinical Trials in Gastric Cancer
The optimal treatment of esophageal cancer is still being defined. The timing of surgical management and the application of chemotherapy and radiation in the neoadjuvant and adjuvant settings have been…
An Update on Randomized Clinical Trials in Melanoma
Despite many advances in the treatment of melanoma, it still continues to be a disease that affects many people. Fortunately, there have been a multitude of randomized trials that have…
The Evolution of Oncology Clinical Research: Lessons Learned
The purpose of clinical research is to add to medical knowledge using hypothesis-driven scientific methods for the betterment of clinical care and for ultimate improvement in patient outcomes. Over the…
Clinical Trials in Surgical Oncology
SURGICAL ONCOLOGY CLINICS OF NORTH AMERICA www.surgonc.theclinics.com Consulting Editor NICHOLAS J. PETRELLI October 2017 • Volume 26 • Number 4
Molecular Biology of Leukemias
Chromosomal translocations Genes Comments Involving RARAα t(15;17)(q21;q21) PML DNA binding, cell proliferation RARα Transcription factor t(11;17)(q23;q21) ZBTB16 (PLZF) Zn-finger transcription factor RARα Transcription factor t(5;17)(q32;q21) NPM1 RNA transport/processing RARα Transcription…
Molecular Mechanisms in Non-Hodgkin Lymphoma
(1) Department of Patholog, University of Massachusetts Medical School, Baystate, Springfield, MA, USA (2) Department of Pathology and Laboratory Medicine, University of North Carolina School of Medicine, Chapel Hill, NC,…
