Pathogenesis of Gastric Cancer

Jun 4, 2017 by in ONCOLOGY Comments Off on Pathogenesis of Gastric Cancer

Fig. 6.1 Precursor lesion of intestinal type gastric cancer – dysplasia. (a) Low-grade dysplasia. Pseudostratification of nuclei. Nuclei are elongated and mostly basally orientated. Few mitotic figures. (b) High-grade dysplasia….

read more

Multimodality Therapy in Gastric Cancer

Jun 4, 2017 by in ONCOLOGY Comments Off on Multimodality Therapy in Gastric Cancer

Treatment arms Primary end point Secondary end points MAGIC [3] Surgery alone Epirubicin 50 mg/m2 day 1 5-year OS 5-year PFS Cisplatin 60 mg/m2 day 1 HR 0.75 HR 0.66…

read more

Pathogenesis of Esophageal Cancer

Jun 4, 2017 by in ONCOLOGY Comments Off on Pathogenesis of Esophageal Cancer

Risk factor Risk Tobacco 4–8× Alcohol 1.3–8× Alcohol dehydrogenase 4× Fruits and vegetables 0.53–0.56× Poverty 8× Gastroesophageal reflux 7.7× Obesity 3.1× Helicobacter pylori infection 0.56–1.1× Squamous Cell Carcinoma Worldwide squamous…

read more

HCC

Jun 4, 2017 by in ONCOLOGY Comments Off on HCC

The clinical evaluation and management of HCC require a comprehensive, multidisciplinary approach that involves cancer surveillance and consideration of both surgical and medical therapies. The implementation of such an approach…

read more

Pharmacokinetic Aspects of Regional Tumor Therapy

Jun 4, 2017 by in ONCOLOGY Comments Off on Pharmacokinetic Aspects of Regional Tumor Therapy

PK parameter Dimension Relevance t 1/2zp Time Transfer from blood to deep compartment t 1/2el Time Elimination half-life from the body c max Concentration/volume Peak concentration in blood or tissue…

read more
Get Clinical Tree app for offline access