History of Acute Leukemia
4. Pearson OH, Eliel LP, Rawson RW, et al. ACTH- and cortisone-induced regression of lymphoid tumors in man. Cancer. 1949;2:943–5.PubMed
A History of the Chronic Leukemias
CrossRef 3. Piller G. The history of leukemia: a personal perspective. Blood Cells. 1993;19:521.PubMed 4. Velpeau A. Sur la resorption du puseat sur l’altération du sang dans les maladies clinique…
Etiology and Epidemiology of Chronic Myeloid Leukemia
Time of observation Number of patients Incidence crude Incidence (WSP)a SEER [28] 1998–2000 – – 1.8b 2003–2007 4,653 – 1.7b France [35] 1985–2006 906 – 0.8 Swedish Cancer…
Diagnosis and Treatment of Essential Thrombocythemia and Primary Myelofibrosis
Acute haemorrhage Malignant disease (e.g. carcinoma, Hodgkin and non-Hodgkin lymphoma) Chronic inflammatory disorders (e.g. rheumatoid arthritis, ulcerative colitis) Acute inflammation Post-operation Splenectomy and hyposplenism Marrow recovery from drug suppression, or…
Treatment of Chronic Lymphocytic Leukemia and Related Disorders
Working groups: NCIWG/IWCLL [2] Parameter Diagnosis Lymphocytes (× 109/L) >5; ≥1 B-cell marker (CD19, CD20, CD23) + CD5 Atypical cells (%) (e.g. prolymphocytes) <55 Duration of lymphocytosis At least…
of Hepatocellular Carcinoma: Current Concepts
Ultrasound CT MRI Advantages Low cost Low cost No radiation Availability Availability High contrast resolution Useful for screening and surveillance Quick Liver-specific agents High spatial resolution Functional MRI Highest…
Carcinoma Biology
Fig. 1 IL-6/STAT3 signaling pathway. Shown is a schematic figure of the IL-6/JAK/STAT signaling pathway. Binding of IL-6 to its cognate receptor results in phosphorylation of JAK1/2 with subsequent autophosphorylation of…
for Hepatocellular Carcinoma: The North American Experience
Tumor classification Definition Stage Criteria T0, N0, M0 Not found Stage I T1 T1 One nodule <2.0 cm Stage II T2 T2 One nodule 2.0–5.0 cm; 2 or 3 nodules, all <3.0 cm Stage III T3 T3…
Resection for Hepatocellular Carcinoma in the Noncirrhotic: The Western Experience
Without underlying liver disease With underlying liver disease p value Number 82 124 − Liver disease, n (%) HBV (HBsAg+) HCV (anti-HCV Ab+) NASH Alcoholic liver disease Other −…
Resection of Hepatocellular Carcinoma
Fig. 1 Algorithm for management of transplantable hepatocellular carcinoma at Henri Mondor Hospital, Creteil, France [3] For patients with a solitary HCC<5 cm, no evidence of extrahepatic tumor burden, compensated liver disease,…
