Liver Tumors
Age at diagnosis (years) 15–19 20–24 25–29 US population (in millions), year 2000 census 19.90 18.70 17.63 Average incidence, 1975–2000, per million 2.0 5.6 14.6 Average annual increase, 1975–2000, SEER…
Soft Tissue Sarcoma
Ewing sarcoma t(11;22)(q24;q12) EWS-FLI1 t(21;22)(q22;q12) EWS-ERG EWS-AFT1 Clear-cell sarcoma t(12;22)(q13;q12) EWS-WT1 Desmoplastic small round cell tumor t(11;22)(q13;q12) EWS-CHN Extraskeletal myxoid chondrosarcoma t(9;22)(q22;q12) TAF2N-CHN TLS-CHOP t(9;17)(q22;q11) TLS-ATF1 PAX3-FKHR Myxoid liposarcoma t(12;16)(q13;p13)…
Thyroid Cancer
Invasive cancer Invasive + In situ cancer Incidencea Thyroid Incidencea Thyroid All sites Thyroid % All sites Thyroid % All ages Male and female 466.4 11.0 2.4 % 522.5…
Acute Lymphoblastic Leukemia
Fig. 7.1 ALL incidence by single years of age, 2000–2012, SEER 18 areas and area-under-the-curve (yellow) that represent “AYA ALL.” The inset shows the same data on an enlarged y-axis…
Breast Cancer Before 40
Fig. 8.1 (a) Proportion of all cancer in females that is breast cancer by single year of age, 2000–2012, SEER18. (b) Incidence of breast cancer in females by single year…
The Biology of AYA Cancers
Fig. 3.1 Incidence of invasive cancer of the colon, rectum, and anus, SEER18, 2000–2012 by age, site, and sex. Age groups with <10 patients excluded. *Includes rectosigmoid junction AYA CRC…
Access and Models of Care
Healthcare system factors Low awareness of AYA cancer in primary care providers Arbitrary referral patterns to pediatric vs. adult medical oncology providers based on age alone Rigid upper age limits…
Testicular Cancer
Fig. 12.1 Incidence and number of men diagnosed with testicular cancer, 2000–2012, SEER18, by single year of age and race/ethnicity (Data from United States National Cancer Institute Surveillance, Epidemiology, and…
Conclusions, Perspectives, and Future Considerations
1. Elucidation of parameters other than age that define the AYA patient 2. Development of and participation in clinical trials benefiting AYA patients 3. Specialization of health services delivery 4….
Acute Myelogenous Leukemia
Fig. 6.1 Incidence of acute myelogenous leukemia (AML) by sex and single years of age in children and AYAs (Surveillance, Epidemiology, and End Results, US SEER 18 regions, 2000–2011) Incidence…
