Patterns and Biology of HPV-Associated HNSCC
First author Year Anatomical site HPV- HPV+ Differently expressed genes (probes) Analyzed genes (probes) Oropharynx Oral cavity Tonsils Base of tongue/tongue Larynx Hypopharynx Keck 2014 X X X 75 55…
Expectations in HNSCC
Cervarix Gardasil Gardasil 9 HPV coverage 16, 18 6, 11, 16, 18 6, 11, 16, 18, 31, 33, 45, 52, 58 Manufacturer GlaxoSmithKline Merck Merck Producing cells Trichoplusia ni…
of HPV Subtypes with Focus on HPV-Infection and Cancer in the Head and Neck Region
Fig. 1 Phylogenetic tree of the HPV16 variants identified by Yamada et al. (1995) in the United States within a sample of 30 HPV16 isolates based on parsimony analysis. Combined sequences…
on De-intensification and Intensification Studies in HPV
© Springer International Publishing Switzerland 2017Wojciech Golusiński, C. René Leemans and Andreas Dietz (eds.)HPV Infection in Head and Neck CancerRecent Results in Cancer Research20610.1007/978-3-319-43580-0_20 Update on De-intensification and Intensification Studies in HPV Hisham Mehanna1, 2 (1)…
Immunology and HPV
© Springer International Publishing Switzerland 2017Wojciech Golusiński, C. René Leemans and Andreas Dietz (eds.)HPV Infection in Head and Neck CancerRecent Results in Cancer Research20610.1007/978-3-319-43580-0_19 Cancer Immunology and HPV Barbara Wollenberg1 (1) Department of Otorhinolaryngology, University of…
Factors for Outcome and Quality of Life in HPV-Positive and HPV-Negative HNSCC
© Springer International Publishing Switzerland 2017Wojciech Golusiński, C. René Leemans and Andreas Dietz (eds.)HPV Infection in Head and Neck CancerRecent Results in Cancer Research20610.1007/978-3-319-43580-0_18 Predictive Factors for Outcome and Quality of Life in HPV-Positive and…
We De-escalate the Treatment for HPV-Positive Tumors?
© Springer International Publishing Switzerland 2017Wojciech Golusiński, C. René Leemans and Andreas Dietz (eds.)HPV Infection in Head and Neck CancerRecent Results in Cancer Research20610.1007/978-3-319-43580-0_13 Should We De-escalate the Treatment for HPV-Positive Tumors? Andreas Dietz1, 2 , Gunnar Wichmann1,…
Radiotherapy in HPV-Associated Oropharyngeal Cancer Patients
Fig. 1 NTCP values (risk on side effects) according to the 6 different approaches. CRT-70 current standard chemoradiation; BioRT-70 standard radiotherapy with cetuximab; CRT-56 reduced radiation dose chemoradiation; CPT-70 standard radiation…
Treatment in HPV-Induced Recurrent or Metastatic HNSCC
Study Method Tested Positive (%) Citation SPECTRUM P16 443 99 (22 %) Vermorken et al., Lancet Oncol (2013) EXTREME P16 381 41 (12 %) Vermorken et al., Ann Oncol (2014) EXTREME HPV…
Papillomavirus (HPV): A Criterion for Therapeutic Decision in Squamous Cell Carcinoma of the Head and Neck?
Authors Year No.pts Subsite % HPV Treatment HR Gillison et al. 2000 252 H&N 25 Surg a/o RT 0.40 Licitra et al. 2006 90 OPC 19 Surg ± RT 0.26 Fakhry et…
