Figure 5.1 Mechanisms of glioma-media immunosuppression. Glioma cells produce immunosuppressive cytokines (interleukin-10 [IL-10] and tumor growth factor-beta [TGF-β]) that downregulate the antitumor activity of T cells and natural killer (NK)…
Figure 7.1 (a) Diffuse astrocytomas are infiltrative tumors with fibrillar cytoplasm and mildly pleomorphic nuclei. (b) The cytoplasm of diffuse astrocytomas is generally immunoreactive for glial fibrillary acidic protein, though cell borders…
Figure 3.1 Sample patient immobilization and field set-up for whole-brain radiotherapy (WBRT) via opposed lateral fields. (a) Custom headholder with field shape outlined on mask; (b) multileaf collimator outline (dark…
html xmlns=”http://www.w3.org/1999/xhtml” xmlns:mml=”http://www.w3.org/1998/Math/MathML” xmlns:epub=”http://www.idpf.org/2007/ops”> 2 Glioma surgery Kyle G. Halvorson and Allan H. Friedman Précis Definition of terms Extent of resection: estimated volume of remaining tumor tissue present on postoperative…
html xmlns=”http://www.w3.org/1999/xhtml” xmlns:mml=”http://www.w3.org/1998/Math/MathML” xmlns:epub=”http://www.idpf.org/2007/ops”> 4 Chemotherapy for gliomas Annick Desjardins and Henry S. Friedman Précis Definition of terms Blood–brain barrier: highly selective permeability barrier that separates the circulating blood from…
Figure 8.1 Binomial, normal, and exponential curves. (a) The binomial distribution is the discrete probability distribution for the number of successes in a sequence of n independent success/failure experiments, each…
html xmlns=”http://www.w3.org/1999/xhtml” xmlns:mml=”http://www.w3.org/1998/Math/MathML” xmlns:epub=”http://www.idpf.org/2007/ops”> 9 Health-related quality of life in glioma patients Katherine B. Peters Précis Definition of terms Health-related quality of life (HRQoL): for patients suffering from a chronic…
(1) Daytona Beach Shores, FL, USA Beneath it [the cancer cell] there must exist some more intimate element which science would need in order to define the nature of…
(1) Daytona Beach Shores, FL, USA Clouds cannot cover secret places, nor denials conceal truth. – Demosthenes The cost of cancer in the United States, in terms of human…
(1) Daytona Beach Shores, FL, USA Insanity: doing the same thing over and over again and expecting different results. – Albert Einstein What has the cell-kill paradigm and its…
