Fig. 17.1 (a) Schematic diagram showing folate-targeted nanoparticle (FNP) containing siRNA. (b) Transmission electron microscopy showing that HuR-FNPs are uniform in size and shape and do not show aggregation Fig….
Fig. 14.1 Percentage apoptosis in primary ovarian cancer cells on treatment with metformin and chemotherapeutic agents In this study, we investigated whether metformin could induce apoptosis in ovarian cancer cells….
Primary tumor (T) TX Primary tumor cannot be assessed T0 No evidence of primary tumor Tis Carcinoma in situ T1 Tumor invades lamina propria or muscular layer T1a Tumor invades…
Fig. 10.1 Estimated age-standardized rates (world) per 100,000 incidence and mortality of cancer in more and less developed countries (GLOBOCAN 2012) 10.2 Indian Scenario With an estimated burden of over…
Fig. 23.1 Inhibition of tumorsphere formation by CQ Conclusions Since small subpopulations of CSCs were identified from blood mononuclear cells in human acute myeloid leukemia in 1997, it has attracted…
Fig. 7.1 Overexpression of TG2 (left panel) in epithelial cells (shown are MCF10A mammary epithelial cells) is associated with their transdifferentiation into mesenchymal looking cells (EMT; a), increased invasion (through…
Fig. 4.1 Illustration of microenvironmental factors involved in CLL survival 4.3 Role of Apoptosis Pathway Members in CLL Pathophysiology Based on their structure and/or functional homology, major protein groups of…
Fig. 16.1 Schematic representation of the mitochondrial respiratory chain The concept of ‘aerobic glycolysis’ suggested by Warburg implies that cancer cells predominantly depend on glycolysis for energy production and to…
Fig. 22.1 Medicinal plants used in traditional Korean medicine for cancer prevention and therapy According to the theory of TKM, common causes that impede healthy living are an excess of…
© Springer International Publishing Switzerland 2015Varsha Gandhi, Kapil Mehta, Rajesh Grover, Sen Pathak and Bharat B. Aggarwal (eds.)Multi-Targeted Approach to Treatment of Cancer10.1007/978-3-319-12253-3_21 21. Chemopreventive and Anticancer Efficacy of Silibinin Against Colorectal Cancer Sushil Kumar1, Komal Raina1, 2 and Rajesh Agarwal1,…
