Hodgkin Lymphoma
Hodgkin Lymphoma Shruti Chaturvedi David S. Morgan I. INTRODUCTION Hodgkin lymphoma (HL) is an uncommon lymphoproliferative malignancy with approximately 9,000 cases diagnosed annually in the United States. The average age…
Myeloproliferative Neoplasms and Myelodysplastic Syndromes
Myeloproliferative Neoplasms and Myelodysplastic Syndromes Jad Chahoud Srdan Verstovsek Guillermo Garcia-Manero Hagop M. Kantarjian Elias Jabbour I. BCR-ABL1-NEGATIVE MYELOPROLIFERATIVE NEOPLASMS A. Overview The myeloproliferative neoplasms (MPNs) are clonal disorders of…
Chronic Leukemias
Chronic Leukemias Chaitra Ujjani Bruce D. Cheson I. INTRODUCTION Although the chronic leukemias have traditionally been grouped together to underscore their differences from the aggressive, acute leukemias, they are a…
Acute Leukemias
Acute Leukemias Ashwin Kishtagari Olga Frankfurt Martin S. Tallman I. GENERAL FEATURES OF ACUTE LEUKEMIAS The acute leukemias are a heterogeneous group of disorders characterized by clonal proliferation and abnormal…
Bone Sarcomas
Bone Sarcomas Jean-Yves Blay Olivia Bally I. INCIDENCE AND NOSOLOGY Bone sarcomas account for about 10% of all sarcomas, and, therefore, 0.1% to 0.2% of all malignant tumors in adult…
Soft-Tissue Sarcomas
Soft-Tissue Sarcomas Jean-Yves Blay Olivia Bally Jean-Michel Coindre I. EPIDEMIOLOGY OF SOFT-TISSUE AND VISCERAL SARCOMAS Soft-tissue and visceral sarcomas are a group of malignant diseases characterized by neoplastic proliferation of…
Primary and Metastatic Brain Tumors
Primary and Metastatic Brain Tumors Muhammad O. Chohan Gregory N. Gan Olivier Rixe I. PRIMARY BRAIN TUMORS A. Epidemiology, risk factors, and survival Primary brain tumors (PBT) constitute a wide…
Melanomas and Other Cutaneous Malignancies
Melanomas and Other Cutaneous Malignancies Ragini Kudchadkar Jeffrey S. Weber I. INTRODUCTION More than two million Americans were diagnosed with skin cancer in 2014, making it the most common malignancy…
Endocrine Cancers
Endocrine Cancers Jaydira del Rivero Antonio Tito Fojo I. THYROID CARCINOMA A. Incidence1,2,3 The incidence of thyroid cancer is rising in both men and women. The National Cancer Institute has…
Kidney Cancer
Kidney Cancer David M.J. Hoffman Rekha A. Kumbla Robert A. Figlin I. RENAL CELL CARCINOMA (RCC) Known as “the internist’s tumor” for its diverse clinical manifestations, advances in the understanding…
