NONTHYROIDAL ANTERIOR CERVICAL NECK MASSES
NONTHYROIDAL ANTERIOR CERVICAL NECK MASSES Part of “CHAPTER 38 – NONTOXIC GOITER“ The thyroidal origin of neck masses is usually apparent from their location and their movement with the thyroid…
CLINICAL FEATURES OF NONTOXIC GOITER
CLINICAL FEATURES OF NONTOXIC GOITER Part of “CHAPTER 38 – NONTOXIC GOITER“ HISTORY AND PHYSICAL FINDINGS Patients with nontoxic goiter have no systemic symptoms, and the goiter is usually found…
SPECIFIC ETIOLOGIES OF GOITER
SPECIFIC ETIOLOGIES OF GOITER Part of “CHAPTER 38 – NONTOXIC GOITER“ CONGENITAL GOITER Congenital goiter is either familial—that is, an expression of genetic disorders of intrathyroidal hormonogenesis (see Chap. 47)—or…
PATHOGENESIS OF NONTOXIC GOITER
PATHOGENESIS OF NONTOXIC GOITER Part of “CHAPTER 38 – NONTOXIC GOITER“ Nontoxic goiter is the result of an interplay of factors intrinsic and extrinsic to the thyroid. In most patients,…
NONTOXIC GOITER
NONTOXIC GOITER Paul J. Davis Faith B. Davis Goiter (L. guttur, throat) is a clinical term denoting thyroid gland enlargement to twice normal size or larger (see also ref. 1)….
IODINE-INDUCED AUTOIMMUNITY
IODINE-INDUCED AUTOIMMUNITY Part of “CHAPTER 37 – ADVERSE EFFECTS OF IODIDE“ Investigators have speculated that increased iodine intake may contribute to the prevalence of autoimmune thyroid disease. Individuals with Hashimoto…
IODIDE-INDUCED THYROTOXICOSIS
IODIDE-INDUCED THYROTOXICOSIS Part of “CHAPTER 37 – ADVERSE EFFECTS OF IODIDE“ The occurrence of hyperthyroidism after iodide administration has been reported throughout the world since this element was first used…
IODINE-INDUCED GOITER AND HYPOTHYROIDISM
IODINE-INDUCED GOITER AND HYPOTHYROIDISM Part of “CHAPTER 37 – ADVERSE EFFECTS OF IODIDE“ Iodine-induced goiter was first reported in 1938; since then, >200 cases have been described. Of 154 cases…
MECHANISM OF ACTION OF EXCESS IODIDE
MECHANISM OF ACTION OF EXCESS IODIDE Part of “CHAPTER 37 – ADVERSE EFFECTS OF IODIDE“ When a small amount of iodide (100–250 μg per day) is administered along with the…
IODIDE SOURCES
IODIDE SOURCES Part of “CHAPTER 37 – ADVERSE EFFECTS OF IODIDE“ AVERAGE IODIDE INTAKE The normal thyroid adapts easily to iodide excess or deficiency. Hyperthyroidism or hypothyroidism resulting from abnormal…
