FAMILIAL HYPOCALCIURIC HYPERCALCEMIA

Aug 25, 2016 by in ENDOCRINOLOGY Comments Off on FAMILIAL HYPOCALCIURIC HYPERCALCEMIA

FAMILIAL HYPOCALCIURIC HYPERCALCEMIA Part of “CHAPTER 58 – PRIMARY HYPERPARATHYROIDISM“ FHH is a benign disorder associated with hypercalcemia.113 Differentiating individuals with FHH from those with primary hyperparathyroidism is extremely difficult….

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PARATHYROID CARCINOMA

Aug 25, 2016 by in ENDOCRINOLOGY Comments Off on PARATHYROID CARCINOMA

PARATHYROID CARCINOMA Part of “CHAPTER 58 – PRIMARY HYPERPARATHYROIDISM“ Parathyroid carcinoma is a rare form of primary hyperparathyroidism.108,109 These patients often have hypercalcemia that is more severe than that usually…

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PRIMARY HYPERPARATHYROIDISM DURING PREGNANCY

Aug 25, 2016 by in ENDOCRINOLOGY Comments Off on PRIMARY HYPERPARATHYROIDISM DURING PREGNANCY

PRIMARY HYPERPARATHYROIDISM DURING PREGNANCY Part of “CHAPTER 58 – PRIMARY HYPERPARATHYROIDISM“ Rarely, primary hyperparathyroidism becomes evident during pregnancy.104 Hyperparathyroidism during pregnancy used to be associated with an increased incidence of…

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THERAPY

Aug 25, 2016 by in ENDOCRINOLOGY Comments Off on THERAPY

THERAPY Part of “CHAPTER 58 – PRIMARY HYPERPARATHYROIDISM“ SURGERY In view of the modern clinical profile of primary hyperparathyroidism, not all patients have features that would prompt a recommendation for…

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DIFFERENTIAL DIAGNOSIS

Aug 25, 2016 by in ENDOCRINOLOGY Comments Off on DIFFERENTIAL DIAGNOSIS

DIFFERENTIAL DIAGNOSIS Part of “CHAPTER 58 – PRIMARY HYPERPARATHYROIDISM“ The differential diagnosis of hypercalcemia is covered in Chapter 59, but several points are particularly relevant to the discussion of primary…

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DIAGNOSIS

Aug 25, 2016 by in ENDOCRINOLOGY Comments Off on DIAGNOSIS

DIAGNOSIS Part of “CHAPTER 58 – PRIMARY HYPERPARATHYROIDISM“ The diagnostic hallmarks of primary hyperparathyroidism are hypercalcemia and an elevated level of PTH. Just as a normal circulating PTH concentration is…

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LABORATORY EVALUATION

Aug 25, 2016 by in ENDOCRINOLOGY Comments Off on LABORATORY EVALUATION

LABORATORY EVALUATION Part of “CHAPTER 58 – PRIMARY HYPERPARATHYROIDISM“ The diagnosis of primary hyperparathyroidism depends on laboratory tests. The serum calcium concentration is virtually always elevated. The serum phosphorus value…

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CLINICAL PRESENTATION

Aug 25, 2016 by in ENDOCRINOLOGY Comments Off on CLINICAL PRESENTATION

CLINICAL PRESENTATION Part of “CHAPTER 58 – PRIMARY HYPERPARATHYROIDISM“ Patients with primary hyperparathyroidism may present with one of several clinical pictures: asymptomatic hypercalcemia; bone or stone disease; other recognized complications,…

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CLINICAL MANIFESTATIONS

Aug 25, 2016 by in ENDOCRINOLOGY Comments Off on CLINICAL MANIFESTATIONS

CLINICAL MANIFESTATIONS Part of “CHAPTER 58 – PRIMARY HYPERPARATHYROIDISM“ The signs and symptoms of primary hyperparathyroidism result from the hypercalcemia (see Chap. 59) and the hyperparathyroid state. In primary hyperparathyroidism,…

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ETIOLOGY

Aug 25, 2016 by in ENDOCRINOLOGY Comments Off on ETIOLOGY

ETIOLOGY Part of “CHAPTER 58 – PRIMARY HYPERPARATHYROIDISM“ The cause of primary hyperparathyroidism is known only for a small subset of patients. Patients who had prior irradiation to the neck…

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