PARATHYROID HORMONE RESISTANCE Part of “CHAPTER 60 – HYPOPARATHYROIDISM AND OTHER CAUSES OF HYPOCALCEMIA“ PSEUDOHYPOPARATHYROIDISM TYPE 1 The term pseudohypoparathyroidism (PHP) describes a heterogeneous syndrome characterized by biochemical hypoparathyroidism (i.e.,…
OTHER CAUSES OF HYPOCALCEMIA Part of “CHAPTER 60 – HYPOPARATHYROIDISM AND OTHER CAUSES OF HYPOCALCEMIA“ HYPERPHOSPHATEMIA Hypocalcemia may also occur because of acute or chronic hyperphosphatemia. Plasma phosphate, when elevated,…
SPECIFIC CAUSES OF HYPOCALCEMIA Part of “CHAPTER 60 – HYPOPARATHYROIDISM AND OTHER CAUSES OF HYPOCALCEMIA“ HYPOPARATHYROIDISM A biochemical state of functional hypoparathyroidism occurs either because of failure of secretion of…
SIGNS AND SYMPTOMS OF HYPOCALCEMIA Part of “CHAPTER 60 – HYPOPARATHYROIDISM AND OTHER CAUSES OF HYPOCALCEMIA“ Ionized calcium, rather than total calcium, is the primary determinant of symptoms in patients…
MECHANISMS OF HYPOCALCEMIA Part of “CHAPTER 60 – HYPOPARATHYROIDISM AND OTHER CAUSES OF HYPOCALCEMIA“ Calcium is present in serum in three forms: bound to serum protein (40–45%), complexed to inorganic…
HYPOPARATHYROIDISM AND OTHER CAUSES OF HYPOCALCEMIA Suzanne M. Jan De Beur Elizabeth A. Streeten Michael A. Levine MECHANISMS OF HYPOCALCEMIA SIGNS AND SYMPTOMS OF HYPOCALCEMIA Related posts: REGULATION OF THE…
TREATMENT OF HYPERCALCEMIA Part of “CHAPTER 59 – NONPARATHYROID HYPERCALCEMIA“ Principles of therapy for hypercalcemia should be based on an understanding of its cause, knowledge of its pathophysiology, and careful…
DIFFERENTIAL DIAGNOSIS OF HYPERCALCEMIA Part of “CHAPTER 59 – NONPARATHYROID HYPERCALCEMIA“ Nonparathyroid disorders that may lead to hypercalcemia are listed in Table 59-1. The most common of these is malignancy,…
SIGNS AND SYMPTOMS OF HYPERCALCEMIA Part of “CHAPTER 59 – NONPARATHYROID HYPERCALCEMIA“ Hypercalcemia, through its effect on cellular sodium-potassium adenosine triphosphatase, leads to hyperpolarization of cell membranes. This hyperpolarization or…
NONPARATHYROID HYPERCALCEMIA Andrew F. Stewart Primary hyperparathyroidism is the most common cause of hypercalcemia among nonhospitalized patients (see Chap. 58). This chapter focuses on nonparathyroid causes of hypercalcemia, the most…
