Acute Myeloid Leukemia and Myelodysplastic Syndromes Robert J. Arceci Soheil Meshinchi HISTORICAL BACKGROUND AND DEFINITIONS The myeloid malignancies represent a heterogeneous group of acute and chronic clonal disorders that arise…
Acute Lymphoblastic Leukemia Karen R. Rabin Maria M. Gramatges Judith F. Margolin David G. Poplack INTRODUCTION Advances in the study and treatment of pediatric acute lymphoblastic leukemia (ALL) are often…
Maximizing Safety in Cancer Treatment Brigitta U. Mueller Amy L. Billett INTRODUCTION In 1980, the American Society of Anesthesiologists was the first professional group to form a patient safety committee…
Cancer Clinical Trials: Design, Conduct, Analysis, and Reporting Susan G. Hilsenbeck Lisa R. Bomgaars Stacey L. Berg Outcomes for many forms of childhood cancer have improved greatly over the past…
Hematopoietic Stem Cell Transplantation in Pediatric Oncology Stephen Gottschalk Swati Naik Meenakshi Hegde Catherine M. Bollard Robert A. Krance Helen E. Heslop INTRODUCTION Hematopoietic stem cell transplantation (HSCT) is an…
Adolescents and Young Adults with Cancer Leonard S. Sender Marcio H. Malogolowkin Keri B. Zabokrtsky ADOLESCENTS AND EMERGING ADULTS The adolescent and young adult (AYA) oncology movement in the United…
General Principles of Surgery Christopher B. Weldon Thomas E. Hamilton Robert C. Shamberger Surgery remains a critical component in the multimodal therapy of childhood cancer. Accurate staging and successful resection…
Adoptive Cellular Immunotherapy Stephen Gottschalk Cliona M. Rooney Malcolm K. Brenner INTRODUCTION Over the last thirty years, a multidisciplinary approach including chemotherapy, radiation, surgery, and/or hematopoietic stem cell transplantation (HSCT)…
General Principles of Radiation Oncology Ralph P. Ermoian Shannon E. Fogh Steve Braunstein Kavita K. Mishra Larry E. Kun Daphne A. Haas-Kogan Radiation oncology is a clinical discipline focused on…
Molecularly Targeted Therapies and Biotherapeutics Malcolm A. Smith INTRODUCTION With the approval of the BCR-ABL inhibitor imatinib for the treatment of chronic myeloid leukemia (CML) by the Food and Drug…
