Adenovirus Infection
Adenovirus Infection Droplet Precautions Contact Precautions Adenoviruses are a group of viruses that infect the tissue lining the respiratory tract, eyes, intestines, and urinary tract. They cause acute, self-limiting, febrile…
Actinomycosis
Actinomycosis Actinomycosis is a subacute-chronic bacterial infection primarily caused by the gram-positive anaerobic bacillus Actinomyces israelii, which produces granulomatous and suppurative lesions with multiple abscesses. Common sites for infection are…
Acinetobacter Infection
Acinetobacter Infection Contact Precautions Acinetobacter is a group of gram-negative, nonmotile bacteria most commonly found in the soil or water. The bacteria have also been found on the skin of…
Understanding and Preventing Infectious Diseases
Understanding and Preventing Infectious Diseases Despite improved treatment and prevention strategies, including powerful antibiotics, complex vaccines, and modern sanitation practices, infection continues to cause a great deal of serious illness…
Unit III. Combination Chemotherapy Regimens
Unit III. Combination Chemotherapy Regimens The use of combination chemotherapy is well established. Combining agents have allowed the clinician to achieve maximum cell kill while trying to minimize toxicity to…
♦Vinorelbine
♦Vinorelbine (vin-oh-rel-been’) Navelbine Pregnancy Category D Mechanism of Action An antimitotic agent that inhibits microtubule formation by interfering with nucleic acid synthesis. Indications Non-small cell lung cancer, breast cancer, ovarian…
♦Vindesine
♦Vindesine (vin’-de-seen) Eldisine, desacetyl vinblastine Pregnancy Category D Mechanism of Action A vinca alkaloid that binds to tubulin and alters the micro-tubular spindle structure, which leads to cell lysis. Indications…
♦Vincristine
♦Vincristine (vin-kris’-teen) Oncovin, VCR, Vincasar Pregnancy Category D Mechanism of Action A vinca alkaloid that arrests metaphase by binding microtubule protein to the mitotic spindle. Specific for the S phase….