Oncohema Key

PRECOCIOUS PSEUDOPUBERTY Part of “CHAPTER 83 – ADRENOCORTICAL DISORDERS IN INFANCY AND CHILDHOOD“ ETIOLOGY AND CLINICAL CHARACTERISTICS Adrenarche is an “adrenal puberty” during which the adrenal cortex acquires the ability…

HYPERCORTISOLISM Part of “CHAPTER 83 – ADRENOCORTICAL DISORDERS IN INFANCY AND CHILDHOOD“ CLINICAL CHARACTERISTICS Cushing syndrome is the clinical manifestation of excess glucocorticoid. Along with the well-known manifestations in adults,…

ADRENOCORTICAL INSUFFICIENCY Part of “CHAPTER 83 – ADRENOCORTICAL DISORDERS IN INFANCY AND CHILDHOOD“ PRIMARY FORM ETIOLOGY Congenital Adrenal Hyperplasia and Hypoplasia. The most prevalent cause of adrenocortical insufficiency in infancy…

GENERAL PRINCIPLES Part of “CHAPTER 83 – ADRENOCORTICAL DISORDERS IN INFANCY AND CHILDHOOD“ Alo-ng with the well-known perturbations of fluid, electrolyte, and glucose homeostasis, adrenocortical diseases that occur in children…

ADRENOCORTICAL DISORDERS IN INFANCY AND CHILDHOOD Robert L. Rosenfield Ke-Nan Qin GENERAL PRINCIPLES ADRENOCORTICAL INSUFFICIENCY

ENDOCRINE ASPECTS OF HYPERTENSION Dalila B. Corry Michael L. Tuck SPECTRUM OF HYPERTENSION Hypertension is an extremely common disorder, affecting 15% to 20% of the population. More than 95% of…

MINERALOCORTICOID RESISTANCE Part of “CHAPTER 81 – HYPOALDOSTERONISM“ Mineralocorticoid resistance implies a lack of response to aldosterone despite its presence. Aldosterone binds to intracellular mineralocorticoid receptors, which interact with DNA….

ISOLATED HYPOALDOSTERONISM Part of “CHAPTER 81 – HYPOALDOSTERONISM“ Isolated hypoaldosteronism, a selective deficiency of aldosterone secretion without alteration in cortisol production, results in a persistent hyperkalemia, which may be associated…

HYPOALDOSTERONISM James C. Melby ISOLATED HYPOALDOSTERONISM

BARTTER SYNDROME Part of “CHAPTER 80 – HYPERALDOSTERONISM“ CLINICAL FEATURES AND PATHOPHYSIOLOGY Bartter syndrome includes a number of disorders of tubular transport that may be familial or acquired as a…