ENDOCRINOLOGY
von Basedow
Karl Adolph von Basedow. Fig. 1 Map of Germany, indicating Dessau, von Basedow’s hometown, and Merseburg, the town where he practiced as a family physician and was laid to rest…
de Quervain
Fritz de Quervain, MD Fritz de Quervain is regarded as one of the last surgical giants, and his obituary appeared in Nature after his death on January 24, 1940 [1]….
and Thyroiditis
Nervousness Heat intolerance Insomnia Anxiety Hyperhidrosis Weight loss Fatigue Muscle weakness Decreased menstrual flow Palpitations Signs Tachycardia Ophthalmopathy Dermopathy (pretibial myxedema) Proximal muscle weakness Diffuse goiter (+ /- bruit) Fine…
James Graves
Robert James Graves. (Etching by Sherman & Smith. Image from the History of Medicine (NLM)) As a lecturer Professor Graves was endowed with peculiar capabilities. To a remarkable person he…
Post-transcriptional Regulation of Luteinizing Hormone Receptor mRNA Expression in the Ovary
Fig. 4.1 LHR mRNA levels during hCG-induced downregulation. Northern blot analysis of steady state LHR mRNA levels in total RNA, isolated at the indicated times, from the ovaries of saline-injected…
Post-transcriptional Regulation of Glucocorticoid Function
Fig. 13.1 Mechanisms of GC action discussed in this review. GCs exert their anti-inflammatory action through multiple mechanisms mediating coordinate changes in gene expression (see text). Regulation of inflammatory responses…
Mechanisms of Post-transcriptional Gene Regulation
Fig. 1.1 Translation initiation and common mechanisms of regulation. The steps of translation initiation are outlined in (a). The ternary complex is comprised of eIFs 1, 1A, 3 and 5…
Post-transcriptional Regulation of Parathyroid Hormone Gene Expression in Health and Disease
Fig. 11.1 Calcium , phosphate , PTH, FGF23, 1,25D and FGF23 interactions. There are endocrinological feedback loops that govern mineral homeostasis. FGF23, fibroblast growth factor 23; PTH, parathyroid hormone ,…
