Fig. 2.1 Hobnail (micropapillary) variant of papillary thyroid carcinoma. This variant typically shows a variable combination of papillary (a), micropapillary (b) and follicular growth pattern (c). Both the papillae and…
Fig. 3.1 Oncocytic (Hürthle cell, oxyphilic) tumour with clear cell features. Benign (a) and malignant oncocytic follicular tumours have abundant granular eosinophilic cytoplasm due to the accumulation of innumerable abnormal…
Chromosomal location Gene Thyroid tumour/s Additional lesions 19p13.11 GRIM-19 (NDUFA13) Multifocal Hürthle cell (oncocytic) adenoma, PTC and/or FTC 19p13.2 TCO (unknown) Multifocal Hürthle cell (oncocytic) adenoma, PTC and/or FTC 1q21…
Fig. 4.1 Poorly differentiated thyroid carcinoma (PDTC) . This case of PDTC discloses solid growth pattern, foci of necrosis and invasion of the capsule (a), as well as invasion of…
© Springer International Publishing AG 2018José Manuel Cameselle-Teijeiro, Catarina Eloy and Manuel Sobrinho-Simões (eds.)Rare Tumors of the Thyroid Glandhttps://doi.org/10.1007/978-3-319-61182-2_1 1. Introduction Manuel Sobrinho-Simões1, 2, 3, 4 , Catarina Eloy1, 2, 3 , Isabel Amendoeira1, 4 , Paula Soares1, 2, 3 , Javier Caneiro-Gómez5 , Miguel Melo1, 2,…
© Springer International Publishing AG 2018José Manuel Cameselle-Teijeiro, Catarina Eloy and Manuel Sobrinho-Simões (eds.)Rare Tumors of the Thyroid Glandhttps://doi.org/10.1007/978-3-319-61182-2_7 7. Therapeutic Options Miguel Melo1, 2, 3 , José M. Cameselle-Teijeiro4, 5, 6 , Catarina Eloy1, 7 , Isabel Amendoeira1, 8 , Paula Soares1, 7 , Javier Caneiro-Gómez9 and…
Fig. 18.1 Mutations in a number of genes can lead to a variety of syndromes of dysgenesis involving the Müllerian or Wolffian ducts, gonads, kidneys, and adrenal glands as a result…
Fig. 20.1 Gonocyte transformation in the first year of life is an incomplete process, with many germ cells failing to transform and then undergoing apoptosis. It is quite possible that this…
Fig. 9.1 Symptomless neck mass Fig. 9.2 Incidental finding on chest X-ray The abdomen accounts for 60% of the primary tumours half of these arise in the suprarenal gland. A further 15%…
Stage Characteristics 1 Pre-adolescent: Elevation of breast papilla/nipple 2 Breast bud stage: Elevation of the breast and papilla as small mound and enlargement of areola 3 Further enlargement of breast…
