Screening for hyperglycemia in pregnancy
BACKGROUND The questions posed in the case history have been addressed in several studies. Not all studies have reached the same conclusions about the same issue. Some have questioned the…
The placenta in diabetes in pregnancy
NORMAL DEVELOPMENT The placenta is a complex organ that is essential for fetal growth and development. It fulfils a wide spectrum of functions, among which the transport of maternal fuels…
Insulin regimens in pregnancy
BACKGROUND Before the advent of insulin in 1922, pregnancy in a woman who had diabetes was uncommon and perinatal mortality rates ranged from 40% to 60%. While the discovery of…
Historical context of hyperglycemia in pregnancy
It is impossible to say how many of the women really had true diabetes mellitus in a severe form, as the data are lacking, but it is fairly certain that…
