OVERVIEW AND BASIC SCIENCE OF RADIATION ONCOLOGY

1. The Discipline of Radiation Oncology
Edward C. Halperin, David E. Wazer, and Carlos A. Perez

PART A: CANCER BIOLOGY.

2. Biologic Basis of Radiation Therapy
William H. McBride and H. Rodney Withers

3. Molecular Cancer and Radiation Biology
Michael Baumann, Nils Cordes, Mechthild Krause, and Daniel Zips

4. Molecular Pathophysiology of Tumors
Rakesh K. Jain and Dan G. Duda

5. Smart Radiotherapy
C. Norman Coleman, Eric J. Bernhard, Jacek Capala, Bhadrasain Vikram, and James A. Deye

PART B: MEDICAL RADIATION PHYSICS.

6. Principles of Radiologic Physics and Dosimetry
James A. Purdy

7. Photon External-Beam Dosimetry and Treatment Planning
James A. Purdy and Eric E. Klein

8. Electron-Beam Therapy Dosimetry, Treatment Planning, and Techniques
Eric E. Klein and Rojano Kashani

9. Conformal Radiation Therapy Physics, Treatment Planning, and Clinical Aspects
James A. Purdy

10. Intensity-Modulated Radiation Treatment Techniques and Clinical Applications
K.S. Clifford Chao, Radhe Mohan, Timothy D. Marinetti, and Lei Dong

11. Image-Guided Radiation Therapy
Loren K. Mell, William Y. Song, Todd Pawlicki, and Arno J. Mundt

SECTION II
TECHNIQUES, MODALITIES, AND MODIFIERS IN RADIATION ONCOLOGY

12. Altered Fractionation Schedules
Anesa Ahamad

13. Late Effects and QUANTEC
John P. Kirkpatrick, Michael T. Milano, Louis S. Constine, Zeljko Vujaskovic, and Lawrence B. Marks

14. Methodology of Clinical Trials
Yaacov Richard Lawrence, James J. Dignam, and Maria Werner-Wasik

15. Total-Body and Hemibody Irradiation
Kenneth B. Roberts, Zhe Chen, and Stuart Seropian

16. Stereotactic Radiosurgery and Radiotherapy
John C. Flickinger and Ajay Niranjan

17. Stereotactic Irradiation of Tumors Outside the Central Nervous System
Brian D. Kavanagh, Jeffrey D. Bradley, and Robert D. Timmerman

18. Intraoperative Radiotherapy
Timothy J. Kinsella

19. Proton Therapy
Nancy Price Mendenhall and Zuofeng Li

20. Carbon Ions
Pascal Pommier, Stephanie E. Combs, and Tadashi Kamada

21. Methods of Immobilization and Stabilization
Joshua Evans, Edwin Crandley, Bruce Libby, and Stanley Benedict

22. Physics and Biology of Brachytherapy
Jeffrey F. Williamson, X. Allen Li, and David J. Brenner

23. Clinical Applications of Brachytherapy: Low-Dose Rate and Pulsed-Dose Rate
Alexandra J. Stewart, Caroline L. Halloway, and Phillip M. Devlin

24. The Physics and Dosimetry of High–Dose-Rate Brachytherapy
Bruce Thomadsen and Rupak K. Das

25. Clinical Aspects and Applications of High–Dose-Rate Brachytherapy
Subir Nag and Granger R. Scruggs

26. Radioimmunotherapy and Unsealed Radionuclide Therapy
Tod W. Speer

27. Photodynamic Therapy
Harry Quon, Charles B. Simone, II, Keith A. Cengel, Jarod C. Finlay, Timothy C. Zhu, and Theresa M. Busch

28. Radiation Oncology in the Developing World
Timothy P. Hanna

29. Chemical Modifiers of Radiation Response
David S. Yoo and David M. Brizel

30. Oncologic Imaging/Oncologic Anatomy
Christopher R. Kelsey, Junzo P. Chino, Jared D. Christensen, and Lawrence B. Marks

31. Hyperthermia as a Treatment Modality
Mark W. Dewhirst, Paul Stauffer, Zeljko Vujaskovic, Chelsea D. Landon, and Leonard R. Prosnitz

32. Basic Concepts of Chemotherapy and Irradiation Interaction
D. Nathan Kim, Michael Story, and Hak Choy

SECTION III
CLINICAL RADIATION ONCOLOGY

PART A: SKIN

33. Skin
William M. Mendenhall, Anthony A. Mancuso, Jessica M. Kirwan, John W. Werning, and Franklin P. Flowers

PART B: AIDS-RELATED MALIGNANCIES

34. Neoplasms Associated with Acquired Immunodeficiency Syndrome
Bernadine R. Donahue and Jay S. Cooper

PART C: CENTRAL NERVOUS SYSTEM

35. Primary Intracranial Neoplasms
Vinai Gondi, Michael A. Vogelbaum, Sean Grimm, and Minesh P. Mehta

36. Pituitary Gland Cancer
Theodore E. Yaeger

37. Spinal Canal
Jiayi Huang, Cliff Robinson, and Jeff M. Michalski

PART D: HEAD AND NECK

38. Eye and Orbit
Nicholas J. Sanfilippo and Silvia C. Formenti

39. Ear
Tony J.C. Wang and K.S. Clifford Chao

40. Locally Advanced Squamous Carcinoma of the Head and Neck
David M. Brizel and David J. Adelstein

41. Nasopharynx
Benjamin H. Lok, Jeremy Setton, Felix Ho, Nadeem Riaz, Shyam S. Rao, and Nancy Y. Lee

42. Cancer of the Nasal Cavity and Paranasal Sinuses
Steven J. Frank, Anesa Ahamad, and K. Kian Ang

43. Salivary Gland Cancer
Chris H.J. Terhaard

44. Oral Cavity
Rafael R. Mañon, Jeffrey N. Myers, Heath D. Skinner, and Paul M. Harari

45. Oropharynx
Joseph K. Salama, Maura L. Gillison, and David M. Brizel

46. Hypopharynx
Timothy J. Kruser, Hiral K. Shah, Henry T. Hoffman, Nitin A. Pagedar, and Paul M. Harari

47. Laryngeal Cancer
William M. Mendenhall, Anthony A. Mancuso, Robert J. Amdur, and John W. Werning

48. Unusual Nonepithelial Tumors of the Head and Neck
Carlos A. Perez and Wade L. Thorstad

49. Neck Cancer Including Unknown Primary Tumor
William M. Mendenhall, Anthony A. Mancuso, Robert J. Amdur, and John W. Werning

50. Thyroid Cancer
Roi Dagan and Robert J. Amdur

PART E: THORAX

51. Lung Cancer
Ramesh Rengan, Indrin J. Chetty, Roy Decker, Corey J. Langer, William P. O’Meara, and Benjamin Movsas

52. Mediastinal and Tracheal Cancer
Daniel R. Gomez, C. David Fuller, Sravana Chennupati, and Charles R. Thomas, Jr.

53. Esophageal Cancer
Brian G. Czito, Albert S. DeNittis, Manisha Palta, and Christopher G. Willett

54. Tumors of the Heart, Pericardium, and Great Vessels
Lawrence J. Sheplan Olsen, Gregory M.M. Videtic, and Roger M. Macklis

PART F: BREAST

55. Breast Cancer: Stage Tis
David E. Wazer and Douglas W. Arthur

56. Breast Cancer: Early Stage
Sharad Goyal, Thomas A. Buchholz, and Bruce G. Haffty

57. Breast Cancer: Locally Advanced and Recurrent Disease, Postmastectomy Radiation, Systemic Therapies
Thomas A. Buchholz, David E. Wazer, and Bruce G. Haffty

PART G: GASTROINTESTINAL

58. Stomach Cancer
Brian G. Czito, Manisha Palta, and Christopher G. Willett

59. Pancreatic Cancer
Manisha Palta, Christopher G. Willett, and Brian G. Czito

60. Cancer of the Liver and Hepatobiliary Tract
Mirrorer M. Liu, Skye H. Cheng, and Andrew T. Huang

61. Cancer of the Colon and Rectum
Manisha Palta, Christopher G. Willett, and Brian G. Czito

62. Anal Cancer
Bernard J. Cummings and James D. Brierley

PART H: URINARY TRACT

63. Cancer of the Kidney, Renal Pelvis, and Ureter
Hiram A. Gay and Jeff M. Michalski

64. Bladder Cancer
Nicholas James, Richard T. Bryan, Richard Viney, Prashant Patel, and Syed A. Hussain

PART I: MALE GENITOURINARY

65. Low-Risk Prostate Cancer
Michael J. Zelefsky, Megan E. Daly, and Richard K. Valicenti

66. Intermediate- and High-Risk Prostate Cancer
Hans T. Chung and Mack Roach, III

67. Testicular Cancer
Gerard C. Morton

68. Cancer of the Penis and Male Urethra
David B. Mansur

PART J: GYNECOLOGIC

69. Uterine Cervix
Akila N. Viswanathan

70. Endometrial Cancer
Kaled M. Alektiar

71. Ovarian and Fallopian Tube Cancer
Larissa Lee, Ross Berkowitz, and Ursula Matulonis

72. Vaginal Cancer
Josephine Kang and Akila N. Viswanathan

73. Cancer of the Female Urethra
Tony Y. Eng

74. Carcinoma of the Vulva
Junzo P. Chino, Laura J. Havrilesky, and Gustavo S. Montana

PART K: RETROPERITONEUM AND ADRENAL GLAND

75. Retroperitoneal Cancer
Jeffrey C. Buchsbaum, James G. Douglas, Barnali Dasgupta, and Brian D. Lawenda

76. Adrenal Cancer
Filip T. Troicki and John J. Coen

PART L: LYMPHOMA AND HEMATOLOGIC TUMORS

77. Hodgkin Lymphoma
Richard T. Hoppe

78. Non-Hodgkin Lymphomas
Leonard R. Prosnitz, Manisha Palta, and Christopher R. Kelsey

79. Primary Cutaneous Lymphomas
James E. Hansen, Youn H. Kim, Richard T. Hoppe, and Lynn D. Wilson

80. Leukemia
Kenneth B. Roberts, Stuart Seropian, and Peter W. Marks

81. Plasma Cell Myeloma and Plasmacytoma
David C. Hodgson, Joseph Mikhael, and Richard W. Tsang

PART M: BONE AND SOFT TISSUE

82. Osteosarcoma and Other Primary Tumors of Bone
Jaroslaw T. Hepel and Timothy J. Kinsella

83. Soft Tissue Sarcoma (Excluding Retroperitoneum)
Elizabeth H. Baldini

PART N: PEDIATRIC

84. Central Nervous System Tumors in Children
Carolyn R. Freeman, Jean-Pierre Farmer, and Roger E. Taylor

85. Wilms Tumor
John A. Kalapurakal and Patrick R.M. Thomas

86. Neuroblastoma
David B. Mansur and Jeff M. Michalski

87. Rhabdomyosarcoma
John C. Breneman and Sarah S. Donaldson

88. Ewing Tumor
Robert B. Marcus, Jr.

89. Lymphomas in Children
Monika L. Metzger, Hiroto Inaba, Stephanie Terezakis, and Louis S. Constine

90. Unusual Tumors in Children
Christian Carrie and Abraham Kuten

PART O: BENIGN DISEASES

91. Nonmalignant Diseases
Karen M. Winkfield, Jose G. Bazan, Iris C. Gibbs, Tony Y. Eng, and Charles R. Thomas

92. Endovascular Brachytherapy
Ray Lin and Prabhakar Tripuraneni

SECTION IV
PALLIATIVE AND SUPPORTIVE CARE

93. Palliation of Brain and Spinal Cord Metastases
Elizabeth M. Nichols, Roy A. Patchell, William F. Regine, and Young Kwok

94. Palliation of Bone Metastases
William F. Hartsell and Santosh Yajnik

95. Palliation of Visceral Recurrences and Metastases and Treatment of Oligometastatic Disease
Ramji R. Rajendran, Siavash Jabbari, and William F. Hartsell

96. Pain Management
Gary Deng, Amitabh Gulati, and Barrie R. Cassileth

97. Supportive Care and Quality of Life
Gary Deng and Barrie R. Cassileth

SECTION V
ECONOMICS, ETHICS, AND TECHNOLOGY ASSESSMENT

98. Technology Assessment, Outcome Analysis Research, Comparative Effectiveness, and Evidence-Based Radiation Oncology
Carlos A. Perez, Edward C. Halperin, and Yolande Lievens

99. Ethics, Professional Values, and Legal Considerations in Radiation Oncology
Brian D. Kavanagh, Laurie J. Lyckholm, and Jeremy Sugarman

100. Economics of Radiation Oncology
Paul J. Schilling

Index