14 Nuclear and cytoplasmic changes in leukocytes
Hyposegmentation of neutrophils
Description:
Associated with:
Pelger-Hüet anomaly, pseudo-Pelger-Hüet anomaly
Pelger-Hüet anomaly is inherited and affects the majority of granulocytes. Pseudo-Pelger–Hüet is acquired, affects less than 50% of granulocytes and is usually accompanied by other morphologic indications of malignancy such as seen in myeloproliferative or myelodysplastic disorders (see Chapters 17 and 18).
