LIPID DISORDERS AND PREGNANCY
Total serum cholesterol and low-density lipoprotein (LDL) cholesterol levels begin to rise at the end of the first trimester
and eventually reach levels˜150% above prepregnancy levels148 (see Chap. 162, Chap. 163, Chap. 164, Chap. 165 and Chap. 166). High-density lipoprotein (HDL) cholesterol levels increase by 25% to 45% within the first trimester and then decline nearly to prepregnancy levels by term.148 Triglyceride levels begin to rise toward the end of the first trimester and continue to increase, reaching levels three-fold greater than prepregnancy levels by term.148 In patients with preexisting elevations of LDL cholesterol, the increases during pregnancy are exaggerated.148 Although an initial fall in LDL cholesterol and triglycerides occurs within the first few days postpartum, levels may not return completely to their prepregnancy status for several weeks to months.148
and eventually reach levels˜150% above prepregnancy levels148 (see Chap. 162, Chap. 163, Chap. 164, Chap. 165 and Chap. 166). High-density lipoprotein (HDL) cholesterol levels increase by 25% to 45% within the first trimester and then decline nearly to prepregnancy levels by term.148 Triglyceride levels begin to rise toward the end of the first trimester and continue to increase, reaching levels three-fold greater than prepregnancy levels by term.148 In patients with preexisting elevations of LDL cholesterol, the increases during pregnancy are exaggerated.148 Although an initial fall in LDL cholesterol and triglycerides occurs within the first few days postpartum, levels may not return completely to their prepregnancy status for several weeks to months.148
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