Pelvic inflammatory disease
Recommended parenteral regimen A |
|---|
Cefotetan 2 g IV every 12 hours |
OR |
Cefoxitin 2 g IV every 6 hours |
PLUS |
Doxycycline 100 mg orally or IV every 12 hours |
Parenteral treatment can be discontinued 24 hours after a patient improves. Clinical oral therapy with doxycycline 100 mg twice a day to complete 14 days of therapy. |
Recommended parenteral regimen B |
|---|
Clindamycin 900 mg IV every 8 hours |
PLUS |
Gentamicin loading dose IV or IM (2 mg/kg of body weight), followed by a maintenance dose (1.5 mg/kg) every 8 hours. Single daily dosing (3–5 mg/kg) may be substituted. |
Parenteral treatment can be discontinued 24 hours after a patient improves. Oral therapy should then be given to complete 14 days of therapy, either clindamycin 450 mg four times a day or doxycycline 100 mg twice a day. |
Alternative parenteral regimen |
|---|
Ampicillin–sulbactam 3 g IV every 6 hours |
PLUS |
Doxycycline 100 mg orally or IV every 12 hours |
Table 64.2 Oral treatment
