Chronic Lymphocytic Leukemia

VIII.E.001 Del(11)(q23) G-Banding


del(11)(q23) G-banding. Arrow indicates foreshortened long arm of chromosome 11.

VIII.E.002 Del(11)(q23) FISH


del(11)(q23) FISH. Probe for the MLL gene at 11q23. (A) Normal cell. Two fused signals indicating two chromosomes 11 with intact q23 (interphase preparation). (B) Abnormal cell. Only one fused signal reflecting deleted portion of long arm containing 11(q23) on the abnormal chromosome 11 (interphase preparation).

VIII.E.003 T(11;14)(q13;q32) G-Banding


t(11;14)(q13;q32) G-banding. Arrows indicate sites of reciprocal translocation.

VIII.E.004 T(11;14)(q13;q32) FISH


t(11;14)(q13;q32) FISH. Probes for IgH (red signal) on chromosome 14q32 and the CCND1 gene on chromosome 11q13. (A) Normal cell. Two red and two green signals (interphase preparation). (B) Two abnormal cells. Each with one red and one green signal representing normal chromosomes 11 and 14 and each with two fused signals representing the reciprocal translocation (interphase preparation).

Jun 12, 2016 | Posted by in HEMATOLOGY | Comments Off on Chronic Lymphocytic Leukemia

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