Chapter 85 Cancer of the Penis Jonathan E. Heinlen and Daniel J. Culkin Summary of Key Points Incidence • Penile cancer is rare in developed countries, but responsible for a large proportion of solid tumors in males where sanitation and medical care are poor. Biological Characteristics • Most penile cancer is squamous cell carcinoma and many are associated with high-risk human papilloma virus (HPV) infection. • Presentation is typically with localized disease with predictable spread to regional lymph nodes preceding widespread metastasis. Primary Therapy • Penile sparing treatment is indicated for minimally invasive disease • Penectomy remains the standard of care for invasion into corpora or urethra. • Radiation has a growing role in the treatment of small lesions. Adjuvant Therapy • Lymphadenectomy remains an important element of treatment in men with intermediate- and high-risk disease. • Sentinel lymph node biopsy is gaining acceptance using newer techniques Locally Advanced Disease and Palliation • Multimodal therapy is investigational for advanced disease. • Treatment of bladder outlet obstruction is an important consideration Treatment of Metastatic Disease Only gold members can continue reading. Log In or Register to continue Share this:Click to share on Twitter (Opens in new window)Click to share on Facebook (Opens in new window) Related Related posts: Imaging Disorders of Blood Cell Production in Clinical Oncology Rehabilitation of Individuals with Cancer Melanoma Carcinoma of Unknown Primary Adult T-Cell Leukemia-Lymphoma Stay updated, free articles. Join our Telegram channel Join Tags: Abeloffs Clinical Oncology Review Jun 13, 2016 | Posted by admin in ONCOLOGY | Comments Off on Cancer of the Penis Full access? Get Clinical Tree
Chapter 85 Cancer of the Penis Jonathan E. Heinlen and Daniel J. Culkin Summary of Key Points Incidence • Penile cancer is rare in developed countries, but responsible for a large proportion of solid tumors in males where sanitation and medical care are poor. Biological Characteristics • Most penile cancer is squamous cell carcinoma and many are associated with high-risk human papilloma virus (HPV) infection. • Presentation is typically with localized disease with predictable spread to regional lymph nodes preceding widespread metastasis. Primary Therapy • Penile sparing treatment is indicated for minimally invasive disease • Penectomy remains the standard of care for invasion into corpora or urethra. • Radiation has a growing role in the treatment of small lesions. Adjuvant Therapy • Lymphadenectomy remains an important element of treatment in men with intermediate- and high-risk disease. • Sentinel lymph node biopsy is gaining acceptance using newer techniques Locally Advanced Disease and Palliation • Multimodal therapy is investigational for advanced disease. • Treatment of bladder outlet obstruction is an important consideration Treatment of Metastatic Disease Only gold members can continue reading. Log In or Register to continue Share this:Click to share on Twitter (Opens in new window)Click to share on Facebook (Opens in new window) Related Related posts: Imaging Disorders of Blood Cell Production in Clinical Oncology Rehabilitation of Individuals with Cancer Melanoma Carcinoma of Unknown Primary Adult T-Cell Leukemia-Lymphoma Stay updated, free articles. Join our Telegram channel Join Tags: Abeloffs Clinical Oncology Review Jun 13, 2016 | Posted by admin in ONCOLOGY | Comments Off on Cancer of the Penis Full access? Get Clinical Tree
