Assessment





Our nation is aging. By 2030, 20% of the population will be over the age of 65. It is estimated that 1.5 million new cases of cancer were diagnosed in 2009 and over 500,000 cancer-related deaths occurred. Of these, approximately 60% of cancer cases and 70% of cancer-related deaths will occur in individuals aged 60 years and older. As the population ages, it is increasingly important that doctors and oncologists characterize the “functional age” of older patients with cancer in order to tailor treatment decisions and stratify outcomes on the basis of factors other than chronologic age, and develop interventions to optimize cancer treatments.



CASE 4-1

CASE STUDY: Mrs. S


Mrs. S is an 80-year-old woman with a history of hypertension presenting to her primary care provider. She was recently hospitalized and discharged from a skilled nursing facility due to an ankle fracture received as a result of a car accident in which she was the driver. She completed rehabilitation and has since returned home. Prior to the accident, she was living alone. However, her son now checks in on her more frequently and calls her twice a day. At this point, she is also afraid of driving and has been relying on public transportation and family members.


Over the next year, Mrs. S becomes increasingly anxious and depressed. She describes “not feeling well” and weight loss. Lab tests are unremarkable. Her son brings concerns of depression to her primary doctor’s attention and she is started on Citalopram. Repeat clinical breast exams reveal bilateral breast masses, the right greater than the left.




What information from a geriatric assessment would help guide treatment?


Physiologic reserve, functional status, cognition, and comorbidity vary considerably among older adults as a result of the aging process. Given this heterogeneity of factors, a geriatric assessment (GA) may help in managing the older patient with cancer.




Overview of the Geriatric Assessment


A geriatric assessment includes an evaluation of an older individual’s functional status, medical conditions (comorbidities), cognition, nutritional status, psychological state, and social support, as well as a review of the patient’s medications ( Table 4-1 ). A meta-analysis of 28 controlled trials demonstrated that Comprehensive Geriatric Assessment (CGA), if linked to geriatric interventions, reduced early rehospitalization and mortality in older patients through early identification and treatment of problems. The components examined in GA can predict morbidity and mortality in older patients with cancer, and can uncover problems relevant to cancer care that would otherwise go unrecognized. This approach to cancer care can facilitate individualizing the options for cancer management, quality of life, and prognosis.



TABLE 4-1

Components of the Geriatric Assessment








  • Functional Evaluation (Physical Function)




    • Self report



    • Performance-based



    • Gait and balance evaluation




  • Comorbidity



  • Cognitive Function



  • Psychological State (Affective Assessment)



  • Social Support



  • Polypharmacy



  • Nutrition



  • Symptoms



  • Selected Geriatric Syndromes



  • Advanced Care Planning



Three fundamental concepts guide geriatric assessment and the resulting medical management. At the core of geriatric assessment is functional status, both as a dimension to be evaluated and as an outcome to be improved or maintained. The maintenance and restoration of functional status is an essential overriding objective of good geriatric and geriatric oncologic care. A second overarching concept guiding geriatric assessment is prognosis, particularly life expectancy. Finally, geriatric assessment must be guided by patient goals.




Physical Function


Functional Status


Functional status and disability reflect the interactions among multiple medical conditions, physiologic aging, psychosocial support, cognitive impairment, and the overall health and vitality of the individual. Functional evaluation can add a dimension beyond the usual medical assessment, providing information on patient care needs and prognosis.


The choice of functional assessment tool depends upon the characteristics of the population (community-dwelling, hospitalized, nursing home residents) and the level of function being assessed. Function can be assessed by self-report, proxy report, performance-based testing, or a combination of these approaches.


Self-Reported Tools to Measure Functional Status


Activities of Daily Living (ADLs and IADLs, Tables 4-2 and 4-3 )


Most commonly, older adults’ functional status is assessed at two levels: activities of daily living (ADLs) and instrumental activities of daily living (IADLs). ADLs are self-care tasks, such as:



TABLE 4-2

Activities of Daily Living (ADLs)

From Lawton MP, Brody EM. Assessment of older people: self-maintaining and instrumental activities of daily living. Gerontologist 1969, 9:179-186. Copyright by the Gerontological Society of America. Reproduced by permission of the publisher.









































In each category, circle the item that most closely describes the person’s highest level of functioning and record the score assigned to that level (either 1 or 0) in the blank at the beginning of the category.
A. Toilet _____
1.Care for self at toilet completely; no incontinence
2.Needs to be reminded, or needs help in cleaning self, or has rare (weekly at most) accidents
3.Soiling or wetting while asleep more than once a week
4.Soiling or wetting while awake more than once a week
5.No control of bowels or bladder
1
0
0
0
0
B. Feeding _____
1.Eats without assistance
2.Eats with minor assistance at meal times and/or with special preparation of food, or help in cleaning up after meals
3.Feeds self with moderate assistance and is untidy
4.Requires extensive assistance for all meals
5.Does not feed self at all and resists efforts of others to feed him or her
1
0
0
0
0
C. Dressing _____
1.Dresses, undresses, and selects clothes from own wardrobe
2.Dresses and undresses self with minor assistance
3.Needs moderate assistance in dressing and selection of clothes
4.Needs major assistance in dressing but cooperates with efforts of others to help
5.Completely unable to dress self and resists efforts of others to help
1
0
0
0
0
D. Grooming (neatness, hair, nails, hands, face, clothing) _____
1.Always neatly dressed and well-groomed without assistance
2.Grooms self adequately with occasional minor assistance, e.g., with shaving
3.Needs moderate and regular assistance or supervision with grooming
4.Needs total grooming care but can remain well-groomed after help from others
5.Actively negates all efforts of others to maintain grooming
1
0
0
0
0
E. Physical Ambulation _____
1.Goes about grounds or city
2.Ambulates within residence on or about one block distant
3.Ambulates with assistance of (check one)
a ( ) another person, b ( ) railing, c ( ) cane, d ( ) walker, e ( ) wheelchair
1.__Gets in and out without help. 2.__Needs help getting in and out
4.Sits unsupported in chair or wheelchair but cannot propel self without help
5.Bedridden more than half the time
1
0
0
0
0
F. Bathing _____
1.Bathes self (tub, shower, sponge bath) without help
2.Bathes self with help getting in and out of tub
3.Washes face and hands only but cannot bathe rest of body
4.Does not wash self but is cooperative with those who bathe him or her
5.Does not try to wash self and resists efforts to keep him or her clean
1
0
0
0
0

Scoring Interpretation: For ADLs, the total score ranges from 0 to 6. In the above-mentioned categories, only the highest level of function receives a 1; These screens are useful for indicating specifically how a person is performing at the present time. When they are also used over time, they serve as documentation of a person’s functional improvement or deterioration.


TABLE 4-3

Instrumental Activities of Daily Living Scale (IADLs)

From Lawton MP, Brody EM. Assessment of older people: self-maintaining and instrumental activities of daily living. Gerontologist 1969, 9:179–186. Copyright by the Gerontological Society of America. Reproduced by permission of the publisher.





















































In each category, circle the item that most closely describes the person’s highest level of functioning and record the score assigned to that level (either 1 or 0) in the blank at the beginning of the category.
A. Ability to Use Telephone _____
1.Operates telephone on own initiative; looks up and dials numbers
2.Dials a few well-known numbers
3.Answers telephone but does not dial
4.Does not use telephone at all
1
1
1
0
B. Shopping _____
1.Takes care of all shopping needs independently
2.Shops independently for small purchases
3.Needs to be accompanied on any shopping trip
4.Completely unable to shop
1
0
0
0
C. Food Preparation _____
1.Plans, prepares, and serves adequate meals independently
2.Prepares adequate meals if supplied with ingredients
3.Heats and serves prepared meals or prepares meals but does not maintain adequate diet
4.Needs to have meals prepared and served
1
0
0
0
D. Housekeeping _____
1.Maintains house alone or with occasional assistance (e.g., domestic help for heavy work)
2.Performs light daily tasks such as dishwashing, bed making
3.Performs light daily tasks but cannot maintain acceptable level of cleanliness
4.Needs help with all home maintenance tasks
5.Does not participate in any housekeeping tasks
1
1
1
1
0
E. Laundry _____
1.Does personal laundry completely
2.Launders small items; rinses socks, stockings, etc.
3.All laundry must be done by others
1
1
0
F. Mode of Transportation _____
1.Travels independently on public transportation or drives own car
2.Arranges own travel by taxi but does not otherwise use public transportation
3.Travels on public transportation when assisted or accompanied by another
4.Travel limited to taxi or automobile with assistance of another
5.Does not travel at all
1
1
1
0
0
G. Responsibility for Own Medications _____
1.Is responsible for taking medication in correct dosages at correct time
2.Takes responsibility if medication is prepared in advance in separate dosages
3.Is not capable of dispensing own medication
1
0
0
H. Ability to Handle Finances _____
1.Manages financial matters independently (budgets, writes checks, pays rent and bills, goes to bank); collects and keeps track of income
2.Manages day-to-day purchases but needs help with banking, major purchases, etc
3.Incapable of handling money
1
1
0

Scoring Interpretation: For IADLs, the total score ranges from 0 to 8. In some categories, only the highest level of function receives a 1; in others, two or more levels have scores of 1 because each describes competence at some minimal level of function. These screens are useful for indicating specifically how a person is performing at the present time. When they are also used over time, they serve as documentation of a person’s functional improvement or deterioration.





  • bathing



  • dressing



  • toileting



  • maintaining continence



  • grooming



  • feeding



  • transferring



Questions about functional ability may be valuable if posed in reference to recent activities: for example, “Did you dress yourself this morning?” rather than “Do you dress yourself?”


An inability to perform basic ADLs alone implies a higher risk for functional decline, hospitalization, and poor outcomes leading to delirium and or death. Dependency in these tasks, which is present in up to 10% of persons aged 75 years or older, usually requires full-time help at home or placement in a nursing home.


IADLs are tasks that are integral to maintaining an independent household, such as:




  • using the telephone



  • shopping for groceries



  • preparing meals



  • performing housework



  • doing laundry



  • driving or using public transportation



  • taking medications



  • handling finances



Asking “Did you drive here today?” or “When did you last drive? (rather than “Do you drive?”) may elicit a more useful answer. IADLs are more likely than ADLs to be influenced by factors other than capacity, such as cultural and gender roles and learned skills.


Basic ADLs (BADLs) and IADLs are commonly reported as total scores (see Tables 4-2 and 4-3 ). The total score for BADLs is 0 to 6; for IADLs it is 0 to 8. In some categories of IADLs, only the highest level of function receives a 1; in others, two or more levels have scores of 1 because each describes competence at some minimal level of function. When these screens are used over time, they serve as documentation of a person’s functional improvement or deterioration. It is worth noting that the description of the functional capabilities is more important than the number total score, especially when monitoring function over time.


A longitudinal analysis of older adults that characterized functional states between independent in ADLs and mobility, dependent on mobility but independent in ADLs, and dependent in ADLs translated to diminished survival and more of that survival spent in disabled states. For example, the life expectancy of an ADL-disabled 75-year-old is similar to that of an 85-year-old independent person; thus the impact of the disability approximates being 10 years older with much more of the remaining life spent disabled.


Advanced Activities of Daily Living (AADLs)


Advanced activities of daily living represent the highest level of function and are comprised of vocational, social, or recreational activities that reflect personal choice and add meaning and richness to a person’s life. The AADLs include employment, attending church, volunteering, going out to dinner or the theater, participating in physical recreational activities, and the like. Changes in these activities may reflect a precursor to IADL or ADL dysfunction.


Karnofsky and Eastern Cooperative Oncology Group (ECOG) Performance Status (PS)


Traditionally, the oncologist’s assessment of functional status includes an evaluation of Karnofsky or Eastern Cooperative Oncology Group (ECOG) performance status (PS), Table 4-4 . In older adults, particularly those with multiple chronic diseases, the prognostic ability of ECOG-PS may not relate to the specific impact of cancer and may be insensitive to functional impairment. Although 70% to 80% of older adults with cancer present with ECOG PS of 0 to 1 (normal or symptomatic but ambulatory), greater than half require assistance with IADLs. Furthermore, studies have shown that physicians’, nurses’, and patients’ assessments of performance status using these measures may be discordant.



TABLE 4-4

Karnofsky and Eastern Cooperative Group Performance Scales
































































Percentage (%) Karnofsky Performance Scale Score ECOG Performance Scale
100 Normal, no complaints, no evidence of disease 0 Normal activity; asymptomatic
90 Able to carry on normal activity; minor signs or symptoms of disease 1 Symptomatic; fully ambulatory
80 Normal activity with effort; some signs or symptoms of disease
70 Cares for self, unable to carry on normal activity or to do active work 2 Symptomatic; in bed <50% of time
60 Requires occasional assistance, but is able to care for most of his/her needs
50 Requires considerable assistance and frequent medical care 3 Symptomatic; in bed 50% of time; not bedridden
40 Disabled, requires special care and assistance
30 Severely disabled, hospitalization indicated; death not imminent 100% bedridden
20 Very sick, hospitalization indicated; death not imminent 4
10 Moribund, fatal processes, progressing rapidly
0 Dead 5 Dead


Use of Self-Reported Functional Status Measures in Cancer Patients


Older patients with cancer, both during initial diagnosis and as cancer survivors, are more likely to require functional assistance than those without cancer. Functional status may be dependent on cancer stage, with observational studies showing this dependency is more commonly found in hospitalized patients with metastatic disease as compared with patients with nonmetastatic disease. IADL impairment predicted postoperative complications (P = .043) in a series of older adults undergoing cancer-related surgery and functional status predicted risk of treatment-related toxicity in studies of ovarian cancer patients receiving standard cytotoxic chemotherapy. In addition, the need for assistance in IADLs has been reported to correlate with psychological distress in older adults with cancer.


The need for assistance with IADLs has been shown to have the same predictive capability for mortality among older adults with cancer. Functional limitations in cancer survivors also persist.


Because functional status changes over time and is affected by other conditions as well as cancer and by the patient’s social needs, accurate assessments at multiple time points over the course of the cancer patient’s life are valuable in monitoring response to treatment and can provide prognostic information that is useful in short- and long-term care planning. Acute or subacute changes in functional status are important to elicit as they may be a marker of underlying medical illness, including recurrence of cancer, cognitive losses, or other psychosocial issues. Health care providers can promote their patients‘ autonomy by mobilizing appropriate medical, social, and environmental supports.


Performance-Based Instruments of Physical Function


Performance-based instruments can provide additional information beyond an older adult’s self-reported perception of difficulty.


Get-up-and-Go Test


Ambulation is an essential prerequisite for completing many of the activities of daily living and slowing of gait speed is an indicator of future morbidity. For example, gait speeds of 1 m/s or less, and especially those less than 0.6 m/s, predict hospitalization, cognitive impairment, and mortality.


The “Get-up and Go Test” has been recommended. This assessment tool does not require specialized equipment, but uses an armless chair and has the individual stand up from the chair, walk 3 meters and sit back down. ( Table 4-5 ) It can be performed by the physician, nurse, or other trained health care provider. Severe abnormalities are considered present if the subject appears at risk for a fall at any time during the test. The time needed to complete this task is used to score the test; greater than 15 seconds is considered a positive screen. Also, ranges of times required to complete the task correlate with independence in some functional tasks. ( Table 4-5 )



TABLE 4-5

Timed Get-Up and Go Test

Adapted from Podsiadlo D, Richardson S. J Am Geriatrics Soc 1991;39:142-148 and from Susan Friedman, MD, MPH, University of Rochester.









































Examiner asks the patient to:


  • Stand up from a chair (without use of armrests, if possible)



  • Stand still momentarily



  • Walk 10 feet (3 meters)



  • Turn around and walk back to chair



  • Turn and be seated

Factors to note:


  • Sitting balance



  • Imbalance with immediate standing



  • Pace (undue slowness) and stability of walking



  • Excessive truncal sway and path deviation



  • Ability to turn without staggering



  • Observe and time the patient

Positive screen:


  • Time of >15 seconds to complete test

Timed Get Up and Go (secs)
10-19 20-29 30+
Tub or shower transfers Self 59% 60% 23%
Climbs stairs Self 77% 60% 4%
Goes outside alone Yes 82% 50% 15%
Chair transfer Self 100% 93% 62%

Proportion able to complete mobility tasks, according to “Timed Get Up and Go” times





Functional Status


Functional status and disability reflect the interactions among multiple medical conditions, physiologic aging, psychosocial support, cognitive impairment, and the overall health and vitality of the individual. Functional evaluation can add a dimension beyond the usual medical assessment, providing information on patient care needs and prognosis.


The choice of functional assessment tool depends upon the characteristics of the population (community-dwelling, hospitalized, nursing home residents) and the level of function being assessed. Function can be assessed by self-report, proxy report, performance-based testing, or a combination of these approaches.




Self-Reported Tools to Measure Functional Status


Activities of Daily Living (ADLs and IADLs, Tables 4-2 and 4-3 )


Most commonly, older adults’ functional status is assessed at two levels: activities of daily living (ADLs) and instrumental activities of daily living (IADLs). ADLs are self-care tasks, such as:



TABLE 4-2

Activities of Daily Living (ADLs)

From Lawton MP, Brody EM. Assessment of older people: self-maintaining and instrumental activities of daily living. Gerontologist 1969, 9:179-186. Copyright by the Gerontological Society of America. Reproduced by permission of the publisher.









































In each category, circle the item that most closely describes the person’s highest level of functioning and record the score assigned to that level (either 1 or 0) in the blank at the beginning of the category.
A. Toilet _____
1.Care for self at toilet completely; no incontinence
2.Needs to be reminded, or needs help in cleaning self, or has rare (weekly at most) accidents
3.Soiling or wetting while asleep more than once a week
4.Soiling or wetting while awake more than once a week
5.No control of bowels or bladder
1
0
0
0
0
B. Feeding _____
1.Eats without assistance
2.Eats with minor assistance at meal times and/or with special preparation of food, or help in cleaning up after meals
3.Feeds self with moderate assistance and is untidy
4.Requires extensive assistance for all meals
5.Does not feed self at all and resists efforts of others to feed him or her
1
0
0
0
0
C. Dressing _____
1.Dresses, undresses, and selects clothes from own wardrobe
2.Dresses and undresses self with minor assistance
3.Needs moderate assistance in dressing and selection of clothes
4.Needs major assistance in dressing but cooperates with efforts of others to help
5.Completely unable to dress self and resists efforts of others to help
1
0
0
0
0
D. Grooming (neatness, hair, nails, hands, face, clothing) _____
1.Always neatly dressed and well-groomed without assistance
2.Grooms self adequately with occasional minor assistance, e.g., with shaving
3.Needs moderate and regular assistance or supervision with grooming
4.Needs total grooming care but can remain well-groomed after help from others
5.Actively negates all efforts of others to maintain grooming
1
0
0
0
0
E. Physical Ambulation _____
1.Goes about grounds or city
2.Ambulates within residence on or about one block distant
3.Ambulates with assistance of (check one)
a ( ) another person, b ( ) railing, c ( ) cane, d ( ) walker, e ( ) wheelchair
1.__Gets in and out without help. 2.__Needs help getting in and out
4.Sits unsupported in chair or wheelchair but cannot propel self without help
5.Bedridden more than half the time
1
0
0
0
0
F. Bathing _____
1.Bathes self (tub, shower, sponge bath) without help
2.Bathes self with help getting in and out of tub
3.Washes face and hands only but cannot bathe rest of body
4.Does not wash self but is cooperative with those who bathe him or her
5.Does not try to wash self and resists efforts to keep him or her clean
1
0
0
0
0

Scoring Interpretation: For ADLs, the total score ranges from 0 to 6. In the above-mentioned categories, only the highest level of function receives a 1; These screens are useful for indicating specifically how a person is performing at the present time. When they are also used over time, they serve as documentation of a person’s functional improvement or deterioration.


TABLE 4-3

Instrumental Activities of Daily Living Scale (IADLs)

From Lawton MP, Brody EM. Assessment of older people: self-maintaining and instrumental activities of daily living. Gerontologist 1969, 9:179–186. Copyright by the Gerontological Society of America. Reproduced by permission of the publisher.





















































In each category, circle the item that most closely describes the person’s highest level of functioning and record the score assigned to that level (either 1 or 0) in the blank at the beginning of the category.
A. Ability to Use Telephone _____
1.Operates telephone on own initiative; looks up and dials numbers
2.Dials a few well-known numbers
3.Answers telephone but does not dial
4.Does not use telephone at all
1
1
1
0
B. Shopping _____
1.Takes care of all shopping needs independently
2.Shops independently for small purchases
3.Needs to be accompanied on any shopping trip
4.Completely unable to shop
1
0
0
0
C. Food Preparation _____
1.Plans, prepares, and serves adequate meals independently
2.Prepares adequate meals if supplied with ingredients
3.Heats and serves prepared meals or prepares meals but does not maintain adequate diet
4.Needs to have meals prepared and served
1
0
0
0
D. Housekeeping _____
1.Maintains house alone or with occasional assistance (e.g., domestic help for heavy work)
2.Performs light daily tasks such as dishwashing, bed making
3.Performs light daily tasks but cannot maintain acceptable level of cleanliness
4.Needs help with all home maintenance tasks
5.Does not participate in any housekeeping tasks
1
1
1
1
0
E. Laundry _____
1.Does personal laundry completely
2.Launders small items; rinses socks, stockings, etc.
3.All laundry must be done by others
1
1
0
F. Mode of Transportation _____
1.Travels independently on public transportation or drives own car
2.Arranges own travel by taxi but does not otherwise use public transportation
3.Travels on public transportation when assisted or accompanied by another
4.Travel limited to taxi or automobile with assistance of another
5.Does not travel at all
1
1
1
0
0
G. Responsibility for Own Medications _____
1.Is responsible for taking medication in correct dosages at correct time
2.Takes responsibility if medication is prepared in advance in separate dosages
3.Is not capable of dispensing own medication
1
0
0
H. Ability to Handle Finances _____
1.Manages financial matters independently (budgets, writes checks, pays rent and bills, goes to bank); collects and keeps track of income
2.Manages day-to-day purchases but needs help with banking, major purchases, etc
3.Incapable of handling money
1
1
0

Scoring Interpretation: For IADLs, the total score ranges from 0 to 8. In some categories, only the highest level of function receives a 1; in others, two or more levels have scores of 1 because each describes competence at some minimal level of function. These screens are useful for indicating specifically how a person is performing at the present time. When they are also used over time, they serve as documentation of a person’s functional improvement or deterioration.





  • bathing



  • dressing



  • toileting



  • maintaining continence



  • grooming



  • feeding



  • transferring



Questions about functional ability may be valuable if posed in reference to recent activities: for example, “Did you dress yourself this morning?” rather than “Do you dress yourself?”


An inability to perform basic ADLs alone implies a higher risk for functional decline, hospitalization, and poor outcomes leading to delirium and or death. Dependency in these tasks, which is present in up to 10% of persons aged 75 years or older, usually requires full-time help at home or placement in a nursing home.


IADLs are tasks that are integral to maintaining an independent household, such as:




  • using the telephone



  • shopping for groceries



  • preparing meals



  • performing housework



  • doing laundry



  • driving or using public transportation



  • taking medications



  • handling finances



Asking “Did you drive here today?” or “When did you last drive? (rather than “Do you drive?”) may elicit a more useful answer. IADLs are more likely than ADLs to be influenced by factors other than capacity, such as cultural and gender roles and learned skills.


Basic ADLs (BADLs) and IADLs are commonly reported as total scores (see Tables 4-2 and 4-3 ). The total score for BADLs is 0 to 6; for IADLs it is 0 to 8. In some categories of IADLs, only the highest level of function receives a 1; in others, two or more levels have scores of 1 because each describes competence at some minimal level of function. When these screens are used over time, they serve as documentation of a person’s functional improvement or deterioration. It is worth noting that the description of the functional capabilities is more important than the number total score, especially when monitoring function over time.


A longitudinal analysis of older adults that characterized functional states between independent in ADLs and mobility, dependent on mobility but independent in ADLs, and dependent in ADLs translated to diminished survival and more of that survival spent in disabled states. For example, the life expectancy of an ADL-disabled 75-year-old is similar to that of an 85-year-old independent person; thus the impact of the disability approximates being 10 years older with much more of the remaining life spent disabled.


Advanced Activities of Daily Living (AADLs)


Advanced activities of daily living represent the highest level of function and are comprised of vocational, social, or recreational activities that reflect personal choice and add meaning and richness to a person’s life. The AADLs include employment, attending church, volunteering, going out to dinner or the theater, participating in physical recreational activities, and the like. Changes in these activities may reflect a precursor to IADL or ADL dysfunction.


Karnofsky and Eastern Cooperative Oncology Group (ECOG) Performance Status (PS)


Traditionally, the oncologist’s assessment of functional status includes an evaluation of Karnofsky or Eastern Cooperative Oncology Group (ECOG) performance status (PS), Table 4-4 . In older adults, particularly those with multiple chronic diseases, the prognostic ability of ECOG-PS may not relate to the specific impact of cancer and may be insensitive to functional impairment. Although 70% to 80% of older adults with cancer present with ECOG PS of 0 to 1 (normal or symptomatic but ambulatory), greater than half require assistance with IADLs. Furthermore, studies have shown that physicians’, nurses’, and patients’ assessments of performance status using these measures may be discordant.



TABLE 4-4

Karnofsky and Eastern Cooperative Group Performance Scales
































































Percentage (%) Karnofsky Performance Scale Score ECOG Performance Scale
100 Normal, no complaints, no evidence of disease 0 Normal activity; asymptomatic
90 Able to carry on normal activity; minor signs or symptoms of disease 1 Symptomatic; fully ambulatory
80 Normal activity with effort; some signs or symptoms of disease
70 Cares for self, unable to carry on normal activity or to do active work 2 Symptomatic; in bed <50% of time
60 Requires occasional assistance, but is able to care for most of his/her needs
50 Requires considerable assistance and frequent medical care 3 Symptomatic; in bed 50% of time; not bedridden
40 Disabled, requires special care and assistance
30 Severely disabled, hospitalization indicated; death not imminent 100% bedridden
20 Very sick, hospitalization indicated; death not imminent 4
10 Moribund, fatal processes, progressing rapidly
0 Dead 5 Dead




Activities of Daily Living (ADLs and IADLs, Tables 4-2 and 4-3 )


Most commonly, older adults’ functional status is assessed at two levels: activities of daily living (ADLs) and instrumental activities of daily living (IADLs). ADLs are self-care tasks, such as:



TABLE 4-2

Activities of Daily Living (ADLs)

From Lawton MP, Brody EM. Assessment of older people: self-maintaining and instrumental activities of daily living. Gerontologist 1969, 9:179-186. Copyright by the Gerontological Society of America. Reproduced by permission of the publisher.









































In each category, circle the item that most closely describes the person’s highest level of functioning and record the score assigned to that level (either 1 or 0) in the blank at the beginning of the category.
A. Toilet _____
1.Care for self at toilet completely; no incontinence
2.Needs to be reminded, or needs help in cleaning self, or has rare (weekly at most) accidents
3.Soiling or wetting while asleep more than once a week
4.Soiling or wetting while awake more than once a week
5.No control of bowels or bladder
1
0
0
0
0
B. Feeding _____
1.Eats without assistance
2.Eats with minor assistance at meal times and/or with special preparation of food, or help in cleaning up after meals
3.Feeds self with moderate assistance and is untidy
4.Requires extensive assistance for all meals
5.Does not feed self at all and resists efforts of others to feed him or her
1
0
0
0
0
C. Dressing _____
1.Dresses, undresses, and selects clothes from own wardrobe
2.Dresses and undresses self with minor assistance
3.Needs moderate assistance in dressing and selection of clothes
4.Needs major assistance in dressing but cooperates with efforts of others to help
5.Completely unable to dress self and resists efforts of others to help
1
0
0
0
0
D. Grooming (neatness, hair, nails, hands, face, clothing) _____
1.Always neatly dressed and well-groomed without assistance
2.Grooms self adequately with occasional minor assistance, e.g., with shaving
3.Needs moderate and regular assistance or supervision with grooming
4.Needs total grooming care but can remain well-groomed after help from others
5.Actively negates all efforts of others to maintain grooming
1
0
0
0
0
E. Physical Ambulation _____
1.Goes about grounds or city
2.Ambulates within residence on or about one block distant
3.Ambulates with assistance of (check one)
a ( ) another person, b ( ) railing, c ( ) cane, d ( ) walker, e ( ) wheelchair
1.__Gets in and out without help. 2.__Needs help getting in and out
4.Sits unsupported in chair or wheelchair but cannot propel self without help
5.Bedridden more than half the time
1
0
0
0
0
F. Bathing _____
1.Bathes self (tub, shower, sponge bath) without help
2.Bathes self with help getting in and out of tub
3.Washes face and hands only but cannot bathe rest of body
4.Does not wash self but is cooperative with those who bathe him or her
5.Does not try to wash self and resists efforts to keep him or her clean
1
0
0
0
0

Scoring Interpretation: For ADLs, the total score ranges from 0 to 6. In the above-mentioned categories, only the highest level of function receives a 1; These screens are useful for indicating specifically how a person is performing at the present time. When they are also used over time, they serve as documentation of a person’s functional improvement or deterioration.


TABLE 4-3

Instrumental Activities of Daily Living Scale (IADLs)

From Lawton MP, Brody EM. Assessment of older people: self-maintaining and instrumental activities of daily living. Gerontologist 1969, 9:179–186. Copyright by the Gerontological Society of America. Reproduced by permission of the publisher.





















































In each category, circle the item that most closely describes the person’s highest level of functioning and record the score assigned to that level (either 1 or 0) in the blank at the beginning of the category.
A. Ability to Use Telephone _____
1.Operates telephone on own initiative; looks up and dials numbers
2.Dials a few well-known numbers
3.Answers telephone but does not dial
4.Does not use telephone at all
1
1
1
0
B. Shopping _____
1.Takes care of all shopping needs independently
2.Shops independently for small purchases
3.Needs to be accompanied on any shopping trip
4.Completely unable to shop
1
0
0
0
C. Food Preparation _____
1.Plans, prepares, and serves adequate meals independently
2.Prepares adequate meals if supplied with ingredients
3.Heats and serves prepared meals or prepares meals but does not maintain adequate diet
4.Needs to have meals prepared and served
1
0
0
0
D. Housekeeping _____
1.Maintains house alone or with occasional assistance (e.g., domestic help for heavy work)
2.Performs light daily tasks such as dishwashing, bed making
3.Performs light daily tasks but cannot maintain acceptable level of cleanliness
4.Needs help with all home maintenance tasks
5.Does not participate in any housekeeping tasks
1
1
1
1
0
E. Laundry _____
1.Does personal laundry completely
2.Launders small items; rinses socks, stockings, etc.
3.All laundry must be done by others
1
1
0
F. Mode of Transportation _____
1.Travels independently on public transportation or drives own car
2.Arranges own travel by taxi but does not otherwise use public transportation
3.Travels on public transportation when assisted or accompanied by another
4.Travel limited to taxi or automobile with assistance of another
5.Does not travel at all
1
1
1
0
0
G. Responsibility for Own Medications _____
1.Is responsible for taking medication in correct dosages at correct time
2.Takes responsibility if medication is prepared in advance in separate dosages
3.Is not capable of dispensing own medication
1
0
0
H. Ability to Handle Finances _____
1.Manages financial matters independently (budgets, writes checks, pays rent and bills, goes to bank); collects and keeps track of income
2.Manages day-to-day purchases but needs help with banking, major purchases, etc
3.Incapable of handling money
1
1
0

Scoring Interpretation: For IADLs, the total score ranges from 0 to 8. In some categories, only the highest level of function receives a 1; in others, two or more levels have scores of 1 because each describes competence at some minimal level of function. These screens are useful for indicating specifically how a person is performing at the present time. When they are also used over time, they serve as documentation of a person’s functional improvement or deterioration.





  • bathing



  • dressing



  • toileting



  • maintaining continence



  • grooming



  • feeding



  • transferring



Questions about functional ability may be valuable if posed in reference to recent activities: for example, “Did you dress yourself this morning?” rather than “Do you dress yourself?”


An inability to perform basic ADLs alone implies a higher risk for functional decline, hospitalization, and poor outcomes leading to delirium and or death. Dependency in these tasks, which is present in up to 10% of persons aged 75 years or older, usually requires full-time help at home or placement in a nursing home.


IADLs are tasks that are integral to maintaining an independent household, such as:




  • using the telephone



  • shopping for groceries



  • preparing meals



  • performing housework



  • doing laundry



  • driving or using public transportation



  • taking medications



  • handling finances



Asking “Did you drive here today?” or “When did you last drive? (rather than “Do you drive?”) may elicit a more useful answer. IADLs are more likely than ADLs to be influenced by factors other than capacity, such as cultural and gender roles and learned skills.


Basic ADLs (BADLs) and IADLs are commonly reported as total scores (see Tables 4-2 and 4-3 ). The total score for BADLs is 0 to 6; for IADLs it is 0 to 8. In some categories of IADLs, only the highest level of function receives a 1; in others, two or more levels have scores of 1 because each describes competence at some minimal level of function. When these screens are used over time, they serve as documentation of a person’s functional improvement or deterioration. It is worth noting that the description of the functional capabilities is more important than the number total score, especially when monitoring function over time.


A longitudinal analysis of older adults that characterized functional states between independent in ADLs and mobility, dependent on mobility but independent in ADLs, and dependent in ADLs translated to diminished survival and more of that survival spent in disabled states. For example, the life expectancy of an ADL-disabled 75-year-old is similar to that of an 85-year-old independent person; thus the impact of the disability approximates being 10 years older with much more of the remaining life spent disabled.




Advanced Activities of Daily Living (AADLs)


Advanced activities of daily living represent the highest level of function and are comprised of vocational, social, or recreational activities that reflect personal choice and add meaning and richness to a person’s life. The AADLs include employment, attending church, volunteering, going out to dinner or the theater, participating in physical recreational activities, and the like. Changes in these activities may reflect a precursor to IADL or ADL dysfunction.

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Sep 30, 2019 | Posted by in ONCOLOGY | Comments Off on Assessment

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