Acute Myeloid Leukemia in Children

Chapter 25 Acute Myeloid Leukemia in Children



Michael C. Wei, Gary V. Dahl, Howard J. Weinstein



Table 25-1 2008 World Health Organization Classification of Acute Myeloid Leukemia







Acute myeloid leukemia with recurrent genetic abnormalities


Acute myeloid leukemia with t(8;21)(q22;q22); RUNX1-RUNX1T1 (formerly AML1-ETO)

Acute myeloid leukemia with inv(16)(p13.1q22) or t(16;16)(p13.1;q22); CBFB-MYH11

Acute promyelocytic leukemia with t(15;17)(q22;q12); PML-RARA

Acute myeloid leukemia with t(9;11)(p22;q23); MLLT3-MLL

Acute myeloid leukemia with t(6;9)(p23;q34); DEK-NUP214

Acute myeloid leukemia with inv(3)(q21q26.2) or t(3;3(q21;q26.2); RPN1-EVI1

Acute myeloid leukemia (megakaryoblastic) with t(1;22)(p13;q13); RBM15-MKL1

Acute myeloid leukemia with myelodysplasia-related changes


Therapy-related myeloid neoplasms


Acute myeloid leukemia, not otherwise specified

Classify as:

Acute myeloid leukemia, minimally differentiated

Acute myeloid leukemia without maturation

Acute myeloid leukemia with maturation

Acute myelomonocytic leukemia

Acute monoblastic/monocytic leukemia

Acute erythroid leukemia
Pure erythroid leukemia

Erythroleukemia, erythroid/myeloid

Acute megakaryoblastic leukemia

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Jun 12, 2016 | Posted by in HEMATOLOGY | Comments Off on Acute Myeloid Leukemia in Children

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