Vaginitis



Vaginitis


Emmanuel Okon

James W. Myers





  • The term “vaginitis” refers to inflammation of the vagina.


  • Symptoms include itching, irritation, and abnormal vaginal discharge.


  • The presence of abnormal discharge, vulvovaginal discomfort, or both is required for the diagnosis of vaginitis.


  • It accounts for an estimated 3 million office visits.


EPIDEMIOLOGY

















Most common causes of Infectious Vaginitis


Bacterial vaginosis (BV) (40%-50%)


Candidiasis (20%-25%)


Trichomonal vaginitis (15%-20%)


Uncommon causes of infectious vaginitis


Foreign body with secondary infection


Desquamative inflammatory vaginitis (DIV) (clindamycin responsive)


Streptococcal vaginitis (group A), Staphylococcus, human immunodeficiency virus (HIV), Gonorrhea, chlamydia/herpes simplex virus (HSV).


Noninfectious vaginitis


Chemical/irritant (soap, tampons, sanitary napkins, condoms, spermicidal gels, diaphragms, and dyes). Allergic, hypersensitivity, and contact dermatitis (lichen simplex)


Neurodermatitis, traumatic, postpuerperal atrophic vaginitis


Atrophic vaginitis. Idiopathic, malignancy.


Postpuerperal atrophic vaginitis


Desquamative inflammatory vaginitis (corticosteroid responsive). Erosive lichen planus. Collagen vascular disease, Behçet syndrome, pemphigus syndromes.



PREDISPOSING FACTORS



  • Increasing age


  • Sexual activity


  • Hormonal status


  • Poor hygiene


  • Immunologic status


  • Anatomy of the genital area


  • Underlying skin diseases


  • Other factors including damp or tight-fitting clothing, scented detergents and soaps, feminine sprays.



MOST COMMON CAUSES OF VAGINITIS

1. Bacterial Vaginosis (BV)



  • This is usually a result of disruption of normal vaginal flora leading to changes in the concentrations of various microorganisms including a depletion of lactobacilli and a proliferation of other anaerobic bacteria like Gardnerella vaginalis, Prevotella, Mobiluncus spp., Mycoplasma hominis, and Atopobium vaginae (Atopobium species are anaerobic bacteria, gram-positive, rod-shaped, or elliptical found as single elements or in pairs or short chains.) Nevertheless, a positive culture for G. vaginalis should not be considered diagnostic of BV unless other evidence of BV (abnormal pH, odor with 10% KOH, clue cells) are found.


  • There is an increase in vaginal pH caused by decrease in hydrogen peroxide-producing lactobacilli.


  • Anaerobes produce amines, which cause the characteristic fishy odor.


  • 50% of women are asymptomatic.


  • BV is less likely to occur in virgins but still does. Can occur in lesbian couples as well.


  • Prevalence is higher at earlier stages of menstrual cycle.


  • There is an associated increased risk of adverse obstetrical and gynecologic clinical outcomes such as preterm delivery, low birth weight, upper genital tract infections, and pelvic inflammatory disease (PID).



    • Treat symptomatic pregnant women.


    • Consider screening and treating those who have a high risk of prematurity.


    • Decreases risk of prematurity in those who have BV and a history of prematurity in some studies but not others.


    • Treatment for BV before abortion or hysterectomy significantly decreases the risk of postoperative infectious complications.


  • It also increases the risk of acquiring HIV, HSV2, gonorrhea, and chlamydial infection.

2. Candidiasis

Jun 22, 2016 | Posted by in INFECTIOUS DISEASE | Comments Off on Vaginitis

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