Annual vaccination against influenza is recommended for all persons aged 6 months and older, including all adults.
Healthy, nonpregnant adults aged <50 years without high-risk medical conditions can receive either intranasally administered live, attenuated influenza vaccine (Flu-Mist) or inactivated vaccine.
Other persons should receive the inactivated vaccine. Adults aged 65 years and older can receive the standard influenza vaccine or the high-dose (Fluzone) influenza vaccine.
Administer a one-time dose of tetanus, diphtheria, and acellular pertussis (Td/Tdap) to adults aged <65 years who have not received Tdap previously or for whom vaccine status is unknown to replace one of the 10-year Td boosters and as soon as feasible to all (i) postpartum women, (ii) close contacts of infants younger than age 12 months (e.g., grandparents and child-care providers), and (iii) healthcare personnel with direct patient contact.
Table 59-1 Vaccines for Adults
Vaccine
Doses
Recommendation
Comment
Measles-mumpsrubella (MMR)
One or two doses
High-risk groups such as college students, healthcare workers, and international travelers should receive two doses; others should receive one dose.
Adults born before 1956 have innate immunity and do not require vaccine.
Tetanus-diphtheria and tetanus-reduced diphtheria-acellular pertussis (Tdap)
Td every 10 years
All adults should receive a Td every 10 years after completion of primary series.
Adults ages 19 to 64 should receive a single dose of Tdap in place of a Td booster if their last dose of Td was 10 years previously or earlier.
Influenza
One dose every year
All adults every year
Allergic hypersensitivity to egg proteins is a contraindication for vaccine.
Pneumococcal vaccine, polysaccharidea
One or two doses
All adults age ≥65 years of age
Adults 19 through 64 years of age who are smokers or have asthma or any long-term health conditions
Residents of nursing homes or long-term care facilities
A second dose is recommended for people 65 years and older who got their first dose when they were younger than 65 and it has been 5 or more years since the first dose.
Varicella
Two doses 28 days apart
High-risk adults who never had chickenpox or not received chickenpox vaccine
Healthcare professionals, teachers, child-care workers, residents and staff in the long-term care facilities, nonpregnant women of childbearing age, college students
Zoster vaccine
Single dose
Adults 60 years old or older, whether or not the patient reported a prior episode of shingles. Persons with chronic medical conditions may be vaccinated unless a contraindication or precaution exists for their condition.
Not if allergic to neomycin and gelatin, immunocompromised pts, pregnant women, active untreated tuberculosis (until resolved), children, or adolescents
Hepatitis A
Two-dose series
Adults in high-risk groups
High-risk group that includes international travelers, residents of communities with high rates of infection (Native Americans, Alaskan natives, and Pacific Islanders), homosexual and bisexual men, injection-drug users, persons with chronic liver disease, and food handlers
Hepatitis B
Three-dose series at 0, 1, and 6 months
Universal infant vaccination and catch-up vaccination of nonimmune older children, adolescents, and high-risk individuals
High-risk groups include healthcare workers, residents and staff of long-term care facilities or prisons, homosexual or bisexual men or heterosexuals with multiple partners, injection-drug users, recipients of clotting factor concentrates, household or sexual contacts of HBV carriers.
HPV vaccine
Three doses series at 0, 1, and 6 months
For girls ages 11-12 years, with catch-up vaccination for girls and women ages 13-26 years
Advisory Committee on Immunization Practices (ACIP) provided guidance that HPV4 may be given to males aged 9 through 26 years to reduce their likelihood of acquiring genital warts; ACIP does not recommend HPV4 for routine use among males.
Meningococcal vaccine
Two doses. The first dose at 11 or 12 years of age, with a booster dose at age 16
Adolescents 11 through 18 years of age, college freshmen living in dormitories, microbiologists who are routinely exposed to isolates of Neisseria meningitidis, military recruits, people who have terminal complement component deficiencies and have anatomic or functional asplenia
Covers serogroups A, C, Y, and W-135, but not B
a The FDA approved a 13-valent, conjugate pneumococcal vaccine for adults >50 in December 2011 but this has not been added to the vaccine schedule to date.
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