Symptoms, signs, or both
Glucose (mg/dl)
Insulin (µU/ml)
C-peplide (nmol/L)
Proinsulin (pmol/L)
β-Hydroxy -butyrate (nmol/liter)
Glucose increase after glucagon (mg/dl)
Circulating oral hypoglycemic
Antibody to insulin
Diagnostic Interpretation
No
< 55
< 3
< 0.2
< 5
> 2.7
< 25
No
No
Normal
Yes
< 55
» 3
< 0.2
< 5
≤ 2.7
> 25
No
Neg (Pos)
Exogenous insulin
Yes
< 55
≥ 3
≥ 0.2
≥ 5
≤ 2.7
> 25
No
Neg
Insulinoma, NIPHS, PGBH
Yes
< 55
≥ 3
> 0.2
≥ 5
≤ 2.7
> 25
Yes
Neg
Oral hypoglycemic agent
Yes
< 55
» 3
» 0.2a
» 5a
≤ 2.7
> 25
No
Pos
Insulin autoimmune
Yes
< 55
< 3
< 0.2
< 5
≤ 2.7
> 25
No
Neg
IGFb
Yes
< 55
< 3
< 0.2
< 5
> 2.7
< 25