17.1 Rheumatic Disease
17.1.1 Name of Disorder
Systemic lupus erythematosus (SLE).
17.1.2 Clinical Definition
Characterized by a marked production of autoantibodies, SLE usually affects the connective tissues but can involve multiple organ systems, including kidneys, joints, skin, and blood.
17.1.3 Name of Disorder
Juvenile dermatomyositis (JDMS).
17.1.4 Clinical Definition
Characterized by vasculitis under the skin and in the muscles, resulting in skin rash and gradual muscle weakness and fatigue; also frequently involves skin, lungs, heart, joints, and gastrointestinal (GI) tract.
17.1.5 Name of Disorder
Vasculitis.
17.1.6 Clinical Definition
Destructive inflammation in blood vessel walls, which can result in dysfunction of multiple organ systems.
17.1.7 Name of Disorder
Juvenile idiopathic arthritis (JIA).
17.1.8 Clinical Definition
Most prevalent arthritis in children, with onset <16 years of age, characterized by inflammation, pain, stiffness, swelling, warmth, and/or damage/deformity of joints; can also cause altered bone growth.