Chapter 23 Radiation Therapy in the Treatment of Hematologic Malignancies Andrea K. Ng, Peter M. Mauch Preferred Treatment for Early-Stage Non-Hodgkin Lymphoma Early-Stage Diffuse Large B-Cell Lymphoma Treated With Combined Modality Therapy Use of Involved Fields • After a complete remission achieved with six to eight cycles of CHOP or R-CHOP: 36 Gy if initial bulky disease; 30 Gy for the remainder of patients • After three to four cycles of CHOP or R-CHOP: 35 to 40 Gy • After a partial remission: 40 Gy Early-Stage Follicular Grade 1 and 2 Lymphoma Use of Involved or Regional Fields Carefully planned radiation therapy to limited fields with modest doses can significantly reduce the risk for significant damage to the marrow reserve, the risk for developing a treatment-related malignancy, and the risk for long-term toxicity to other normal tissues such as the salivary glands, lungs, heart, kidneys, and bowel. Only gold members can continue reading. Log In or Register to continue Share this:Click to share on Twitter (Opens in new window)Click to share on Facebook (Opens in new window) Related Related posts: Diagnosis and Treatment of Diffuse Large B-Cell Lymphoma and Burkitt Lymphoma Hematologic Manifestations of Cancer Acquired Disorders of Red Cell, White Cell, and Platelet Production Hematology in Aging Disorders of Phagocyte Function Inherited Forms of Bone Marrow Failure Tags: Hematology Diagnosis and Treatment Jun 12, 2016 | Posted by admin in HEMATOLOGY | Comments Off on Radiation Therapy in the Treatment of Hematologic Malignancies
Chapter 23 Radiation Therapy in the Treatment of Hematologic Malignancies Andrea K. Ng, Peter M. Mauch Preferred Treatment for Early-Stage Non-Hodgkin Lymphoma Early-Stage Diffuse Large B-Cell Lymphoma Treated With Combined Modality Therapy Use of Involved Fields • After a complete remission achieved with six to eight cycles of CHOP or R-CHOP: 36 Gy if initial bulky disease; 30 Gy for the remainder of patients • After three to four cycles of CHOP or R-CHOP: 35 to 40 Gy • After a partial remission: 40 Gy Early-Stage Follicular Grade 1 and 2 Lymphoma Use of Involved or Regional Fields Carefully planned radiation therapy to limited fields with modest doses can significantly reduce the risk for significant damage to the marrow reserve, the risk for developing a treatment-related malignancy, and the risk for long-term toxicity to other normal tissues such as the salivary glands, lungs, heart, kidneys, and bowel. Only gold members can continue reading. Log In or Register to continue Share this:Click to share on Twitter (Opens in new window)Click to share on Facebook (Opens in new window) Related Related posts: Diagnosis and Treatment of Diffuse Large B-Cell Lymphoma and Burkitt Lymphoma Hematologic Manifestations of Cancer Acquired Disorders of Red Cell, White Cell, and Platelet Production Hematology in Aging Disorders of Phagocyte Function Inherited Forms of Bone Marrow Failure Tags: Hematology Diagnosis and Treatment Jun 12, 2016 | Posted by admin in HEMATOLOGY | Comments Off on Radiation Therapy in the Treatment of Hematologic Malignancies
