Prevention of Viral Hepatitis



Prevention of Viral Hepatitis


Zhi Q. Yao



HEPATITIS A



  • Since hepatitis A is transmitted primarily by the fecal-oral route, on contaminated hands, or in food and water sources, personal hygiene is critical in prevention of viral spread.


  • An inactivated HAV vaccine was licensed in 1995, and the FDA recommends that all children should be vaccinated starting at 1 year of age.


  • HAV vaccine efficacy after two doses is 94% to 100%, with protection lasting for at least 20 years.


  • Emergency prevention of hepatitis A consists of hepatitis A immune globulin and hepatitis A vaccine, which should be given to all nonimmune contacts exposed to an infected person.


  • Persons at high risk should also be vaccinated



    • Chronic liver disease


    • Men who have sex with men


    • Travelers to areas of high incidence








Hepatitis A Vaccine Adult Schedule























Vaccine


Dose


Interval


Comment


Havrix


1 mL IM


0 and 6-12 months



Vaqta


1 mL IM


0 and 6-18 months



Twinrix (Hep A/Hep B)


1 mL IM in deltoid


0, 1, and 6 months


Alternative schedule: 0, 7 days, 21-30 days, and 1 year



HEPATITIS B

Jun 22, 2016 | Posted by in INFECTIOUS DISEASE | Comments Off on Prevention of Viral Hepatitis
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