Precursor Lymphoid Neoplasms |
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B lymphoblastic leukemia/lymphoma NOS |
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B lymphoblastic leukemia/lymphoma with recurrent genetic abnormalities |
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t(9:22)(q34;q11.2); BCR-ABL1 |
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t(v;11q23); MLL rearranged |
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t(12:21)(p13;q22); TEL-AML1 (ETV6-RUNX1) |
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With hyperdiploidy |
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With hypodiploidy |
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t(5:14)(q31;q32); IL3-IGH |
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t(1:19)(q23;p13.3); E2A-PBX1(TCF3-PBX1) |
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T lymphoblastic leukemia/lymphoma |
Mature B-Cell Neoplasms |
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SLL/CLL |
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B-cell prolymphocytic leukemia |
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Splenic B-cell MZL |
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Hairy cell leukemia |
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Splenic B-cell lymphoma/leukemia, unclassifiable |
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Splenic diffuse red pulp small B-cell lymphoma |
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Hairy cell leukemia-variant |
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Lymphoplasmacytic lymphoma |
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Heavy-chain diseases |
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Gamma heavy-chain disease |
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Mu heavy-chain disease |
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Alpha heavy-chain disease |
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Plasma cell neoplasms |
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Monoclonal gammopathy of undetermined significance |
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Plasma cell myeloma |
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Solitary plasmacytoma of bone |
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Extraosseous plasmacytoma |
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Monoclonal immunoglobulin deposition diseases |
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Extranodal marginal zone B-cell lymphoma of MALT |
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Nodal marginal zone B-cell lymphoma |
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FL |
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Primary cutaneous follicle center lymphoma |
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Mantle cell lymphoma |
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DLBCL, NOS |
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T-cell/histiocyte-rich large B-cell lymphoma |
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Primary DLBCL of the CNS |
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Primary cutaneous DLBCL, leg type |
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EBV-positive DLBCL of the elderly |
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DLBCL associated with chronic inflammation |
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Lymphomatoid granulomatosis |
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Primary mediastinal (thymic) large B-cell lymphoma |
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Intravascular large B-cell lymphoma |
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ALK+ large B-cell lymphoma |
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Plasmablastic lymphoma |
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Large B-cell lymphoma arising in HHV8-associated multicentric Castleman disease |
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Primary effusion lymphoma |
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BL |
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B-cell lymphoma, unclassifiable, with features intermediate between DLBCL and BL |
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B-cell lymphoma, unclassifiable, with features intermediate between DLBCL and classical Hodgkin lymphoma |
Mature T- and NK-Cell Neoplasms |
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T-cell prolymphocytic leukemia |
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T-cell large granular lymphocyte leukemia |
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Chronic lymphoproliferative disorder of NK cells |
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Aggressive NK-cell leukemia |
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EBV-positive T-cell lymphoproliferative diseases of childhood |
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Systemic EBV+ T-cell lymphoproliferative disease of childhood |
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Hydroa vacciniforme-like lymphoma |
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Adult T-cell lymphoma/leukemia |
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Extranodal NK-/T-cell lymphoma nasal type |
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Enteropathy-associated T-cell lymphoma |
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Hepatosplenic T-cell lymphoma |
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Subcutaneous panniculitis-like T-cell lymphoma |
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Mycosis fungoides (CTCL) |
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Sézary syndrome |
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Primary cutaneous CD30-positive T-cell lymphoproliferative disorders |
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Primary cutaneous PTCLs, rare subtypes |
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Primary cutaneous gamma-delta T-cell lymphoma |
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Primary cutaneous CD8-positive aggressive epidermotropic cytotoxic T-cell lymphoma |
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Primary cutaneous CD4-positive small/medium T-cell lymphoma |
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PTCL-NOS |
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Angioimmunoblastic T-cell lymphoma |
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Anaplastic large-cell lymphoma, ALK+ |
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Anaplastic large-cell lymphoma, ALK– |
Immunodeficiency-Associated Lymphoproliferative Disorders |
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Lymphoproliferative diseases associated with primary immune disorders |
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Lymphomas associated with HIV infection |
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PTLD |
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Plasmacytic hyperplasia and infectious-mononucleosis-like PTLD |
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Polymorphic PTLD |
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Monomorphic PTLD |
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Classical Hodgkin lymphoma-type PTLD |
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Other iatrogenic immunodeficiency-associated lymphoproliferative disorders |
BL, Burkitt lymphoma; CLL, chronic lymphocytic leukemia; CNS, central nervous system; CTCL, cutaneous T-cell lymphomas; DLBCL, diffuse large B-cell lymphoma; EBV, Epstein-Barr virus; FL, follicular lymphoma; HHV8, human herpesvirus 8; HIV, human immunodeficiency virus; MZL, marginal zone lymphoma; NK, natural killer; NOS, not otherwise specified; PTCL, peripheral T-cell lymphomas; PTLD, posttransplant lymphoproliferative disorder; SLL, small lymphocytic lymphoma; WHO, World Health Organization. |