Megakaryocytes

V.E.001 Megakaryocyte

V.E.001

Megakaryocyte. Marrow film. Giant cell with multiple nuclear lobes stained a deep blue to purple. Cytoplasm contains platelet fields with the platelet granules staining blue to purple color. A characteristic clear gray zone encircles the cytoplasmic periphery.

V.E.002 Megakaryocyte, Mature & Immature

V.E.002

Megakaryocyte, mature and immature. Marrow film. On the left, megakaryocyte with multiple nuclear lobes stained a deep blue to purple. Cytoplasm contains platelet fields staining pinkish-purple. On the right is a stage 1 megakaryoblast with a thin rim of basophilic cytoplasm and a round or horseshoe-shaped nucleus occupying most of the cell.

V.E.003 Megakaryocyte, Immature

V.E.003

Megakaryocyte, Immature (stage 1). Marrow film. A stage 1 megakaryoblast with a thin rim of basophilic cytoplasm and a round large nucleus.

V.E.004 Megakaryocyte, Immature

V.E.004

Megakaryocyte, Immature (stage 2). Marrow film. A stage 2 megakaryoblast (promegakaryocyte) with minimal cytoplasm and multiple nuclear lobes (probably four nuclear lobes).

V.E.005 Megakaryocyte

V.E.005

Megakaryocyte. Marrow film. Giant cell with multiple nuclear lobes stained a deep blue to purple. Cytoplasm contains platelet fields with the platelet granules staining blue to purple color. A characteristic clear gray zone encircles the cytoplasmic periphery.

V.E.006 Megakaryocyte

V.E.006

Megakaryocyte. Marrow film. Giant cell with multiple nuclear lobes stained a deep blue to purple. Cytoplasm contains platelet fields with the platelet granules staining blue to purple color.

V.E.007 Megakaryocyte

V.E.007

Megakaryocyte. Marrow film. Giant cell with multiple nuclear lobes stained a deep blue to purple. Cytoplasm staining blue to purple color. Note cytoplasmic pseudopodia projecting from periphery, suggesting the cell was caught in the process of proplatelet release.

V.E.008 Megakaryocyte

V.E.008

Megakaryocyte. Marrow film. Giant cell with multiple nuclear lobes stained a deep blue to purple. Cytoplasm contains platelet fields with the platelet granules staining blue to purple color.