Infectious Mononucleosis and Other Epstein-Barr Virus–Associated Diseases: Part 2

Chapter 22 Infectious Mononucleosis and Other Epstein-Barr Virus–Associated Diseases


Part 2



Carl Allen, Cliona M. Rooney, Stephen Gottschalk



image

Figure 22-1 EBV-LATENT GENE EXPRESSION AND IMMUNOGENICITY OF COMMON EBV-ASSOCIATED MALIGNANCIES.


EBNA, Epstein-Barr nuclear antigen; LP, leader protein. For an explanation of symbols, see Fig. 21-1. *Not all lymphomas are latency type III.



EBV-Associated Malignancies




















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Jun 12, 2016 | Posted by in HEMATOLOGY | Comments Off on Infectious Mononucleosis and Other Epstein-Barr Virus–Associated Diseases: Part 2

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Malignancy EBV Frequency
Hodgkin disease ≈40%
Non-Hodgkin lymphomas  
Burkitt lymphoma 20%-95%
Diffuse large B-cell lymphoma and CD30+ Ki-1+ anaplastic large cell lymphoma 10%-35%