Chapter 46 Indications and Outcome of Allogeneic Hematopoietic Cell Transplantation for Hematologic Malignancies in Adults
Figure 46-1 INDICATIONS FOR ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION IN ADULTS (U.S. DATA), 2009.
Table 46-1 Consensus Definition of Conditioning Regimen Intensity
| Myeloablative Conditioning (MAC) |
|---|
| PROFOUND CYTOPENIA; NOT LIKELY TO RECOVER WITHOUT HEMATOPOIETIC CELL RESCUE |
| Nonmyeloablative |
| MINIMAL CYTOPENIA; AUTOLOGOUS RECOVERY OF HEMATOPOIESIS LIKELY EVEN WITHOUT TRANSPLANT |
| REDUCED-INTENSITY CONDITIONING |
Adapted from Bacigalupo A, Ballen K, Rizzo D, et al: Defining the intensity of conditioning regimens: working definitions. Biol Blood Marrow Transplant 15:1628, 2009.
Table 46-2 Retrospective Registry-Based Comparisons of NMA/RIC vs. Myeloablative Allogeneic Hematopoietic Stem Cell Tansplantation
ALL, Acute lymphoblastic leukemia; AML, acute myeloid leukemia; CIBMTR, Center for International Blood and Marrow Transplant Research; CLL, chronic lymphocytic leukemia; EBMT, European Group for Blood and Marrow Transplantation; HL, Hodgkin lymphoma; KPS, Karnofsky performance score; LFS, leukemia free survival; MAC, myeloablative conditioning; MDS, myelodysplastic syndrome; MM, multiple myeloma; MUD,
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