(ICD‐O‐3 C40, 41)



BONE (ICD‐O‐3 C40, 41)


Rules for Classification


The classification applies to all primary malignant bone tumours except malignant lymphomas, multiple myeloma, surface/juxtacortical osteosarcoma and juxtacortical chondrosarcoma. There should be histological confirmation of the disease and division of cases by histological type and grade.


TNM Clinical Classification


T – Primary Tumour









TX Primary tumour cannot be assessed
T0 No evidence of primary tumour

Appendicular Skeleton, Trunk, Skull and Facial Bones












T1 Tumour 8 cm or less in greatest dimension (Fig. 304, 305)
T2 Tumour more than 8 cm in greatest dimension (Fig. 306, 307)
T3 Discontinuous tumours in the primary bone site (Fig. 308)
Schematic illustration of tumour 8 cm or less in greatest dimension.

Fig. 304

Photo depicts a T1 sarcoma of the tibia 8 cm in greatest dimension.

Fig. 305 T1 sarcoma of the tibia 8 cm in greatest dimension

Schematic illustration of tumour more than 8 cm in greatest dimension.

Fig. 306

Photo depicts a T2 sarcoma of the femur more than 8 cm in greatest dimension.

Fig. 307

Schematic illustration of Discontinuous tumours in the primary bone site.

Fig. 308


Spine


















T1 Tumour confined to a single vertebral segment or two adjacent vertebral segments
T2 Tumour confined to three adjacent vertebral segments
T3 Tumour confined to four adjacent vertebral segments
T4a Tumour invades into the spinal canal
T4b Tumour invades the adjacent vessels or tumour thrombosis within the adjacent vessels

Note
The five vertebral segments (Fig. 309) are:



  • Right pedicle
  • Right body
  • Left body
  • Left pedicle
  • Posterior element

Pelvis



























T1a A tumour no more than 8 cm in size and confined to a single pelvic segment with no extraosseous extension
T1b A tumour greater than 8 cm in size and confined to a single pelvic segment with no extraosseous extension
T2a A tumour no more than 8 cm in size and confined to a single pelvic segment with extraosseous extension or confined to two adjacent pelvic segments without extraosseous extension
T2b A tumour greater than 8 cm in size and confined to a single pelvic segment with extraosseous extension or confined to two adjacent pelvic segments without extraosseous extension
T3a A tumour no more than 8 cm in size and confined to two pelvic segments with extraosseous extension
T3b A tumour greater than 8 cm in size and confined to two pelvic segments with extraosseous extension
T4a Tumour involving three adjacent pelvic segments or crossing the sacroiliac joint to the sacral neuroforamen
T4b Tumour encasing the external iliac vessels or gross tumour thrombus in major pelvic vessels

Note
The four pelvic segments (Fig. 310) are:



  • Sacrum lateral to sacral foramen
  • Iliac wing
  • Acetabulum/periacetabulum
  • Pelvic rami, symphysis and ischium
Schematic illustration of the five vertebral segments Right pedicle, Right body, Left body, Left pedicle, Posterior element.

Fig. 309


Source: From AJCC Cancer Staging Manual 2017. © Springer Nature.

Schematic illustration of The four pelvic segments are: Sacrum lateral to sacral foramen, Iliac wing, Acetabulum/periacetabulum, Pelvic rami, symphysis and ischium.

Fig. 310


Source: From AJCC Cancer Staging Manual 2017. © Springer Nature.


N – Regional Lymph Nodes












NX Regional lymph nodes cannot be assessed
N0 No regional lymph node metastasis
N1 Regional lymph node metastasis

M – Distant Metastasis















M0 No distant metastasis
M1 Distant metastasis

M1a Lung

M1b Other distant sites

pTNM Pathological Classification


The pT and pN categories correspond to the T and N categories.






pM1 Distant metastasis microscopically confirmed

Note
pM0 and pMX are not valid categories.


Summary

Tags:
Dec 15, 2022 | Posted by in ONCOLOGY | Comments Off on (ICD‐O‐3 C40, 41)

Full access? Get Clinical Tree

Get Clinical Tree app for offline access