Change in body shape during the menopausal transition. A decrease in estrogens after menopause, coupled to an increased ratio of androgens to estrogens, has been suggested to impact fat accumulation and accumulation of fat at specific depots (shaded). Namely, premenopausal women tend to accumulate fat subcutaneously around the buttocks and thighs whereas postmenopausal women tend to accumulate fat intra-abdominally