131: Yellow Fever

Classification: ICD-9 060; ICD-10 A95

Syndromes and synonyms: Hemorrhagic fever, jungle yellow fever, urban yellow fever.

Agent: Yellow fever virus (YFV) is an enveloped single-stranded positive-sense RNA virus that belongs to the genus Flavivirus. YFV is genetically more heterogeneous in Africa than in America, suggesting it originated in Africa.

Reservoir: Humans and non-human primates are the main reservoirs.

Vector: Tree-hole-breeding forest mosquitoes: Aedes spp. in Africa, and Haemagogus and Sabethes spp. in South America. Transovarian transmission occurs in the mosquito and may be the way the virus survives in the years between cycles. The urban vector on both continents is Aedes aegypti.

Transmission: By mosquito bite.

Cycle

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