100: Ebola and Marburg Virus Disease

Classification: ICD-9 065.8 and 078.89; ICD-10 A98.4 and A98.3

Syndromes and synonyms: Ebola or Marburg hemorrhagic fever.

Agent: Ebola viruses (genus Ebolavirus), marburg viruses (genus Marburgvirus), and ‘cueva viruses’, family Filoviridae, order Mononegavirales; enveloped, single-stranded, negative-sense RNA viruses. There are five ebola viruses: Bundibugyo virus (BDBV), Ebola virus (EBOV), Reston virus (RESTV), Sudan virus (SUDV), and Taï Forest virus (TAFV); two marburg viruses: Marburg virus (MARV) and Ravn virus (RAVV); and one ‘cuevavirus’: Lloviu virus (LLOV).

Reservoir: Ebola viruses: possibly fruit bats, unknown for BDBV, SUDV, and TAFV; Marburg viruses: infectious MARV and RAVV have been isolated from Egyptian fruit bats; ‘Cuevaviruses’: Schreiber’s long-fingered bats.

Transmission

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