♦Vindesine
(vin’-de-seen)
Eldisine, desacetyl
vinblastine
Pregnancy Category D
Mechanism of Action
A vinca alkaloid that binds to tubulin and alters the micro-tubular spindle structure, which leads to cell lysis.
Indications
Investigational use for head and neck cancer, esophageal cancer, breast cancer, melanoma, non-small cell lung cancer, lymphoma.
Metabolism/Excretion
Metabolized in the liver; excreted in urine and feces.
Dosage Range
Varies depending on patient and disease.