♦Pentostatin

♦Pentostatin
(pen’-toe-stah-tin)
Nipent
Pregnancy Category D
Mechanism of Action
An antitumor antibiotic that inhibits the ADA enzyme and causes cell lysis.
Indications
Alpha-interferon-refractory hairy cell leukemia in adults.
Metabolism/Excretion
Metabolized in the liver; excreted in urine.
Dosage Range
♦ Adult: 4 mg/m2 IV every other week.
♦ Pediatric: Safety and effectiveness not established.

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Jul 20, 2016 | Posted by in ONCOLOGY | Comments Off on ♦Pentostatin

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