♦Pegasparagase
(peg-ass-par’-a-gase)
Oncaspar
Pregnancy Category C
Mechanism of Action
Indications
Acute lymphoblastic leukemia in patients hypersensitive to native forms of L-asparaginase.
Metabolism/Excretion
Small amounts are excreted in urine and bile.
Dosage Range
For adults and children with a body surface area of ≥0.6 m2, 2500 IU/m2 every 14 days. For children with a body surface area of <0.6 m2, 82.5 IU/kg every 14 days.