♦Mitotane
(mye’-toe-tane)
Lysodren
Pregnancy Category C
Mechanism of Action
Unknown. Appears to reduce levels of urinary and plasma adrenocorticosteroids and causes lysis of adrenal cortical cells.
Indications
Adrenal cortex carcinoma.
Metabolism/Excretion
Metabolized in the liver; excreted in urine and bile.