7 Eosinophil maturation

FIGURE 7–1 Eosinophilic sequence—eosinophilic myelocyte.

Eosinophilic myelocyte

FIGURE 7–2A Eosinophilic myelocyte.

FIGURE 7–2B Electron micrograph of eosinophilic granules to demonstrate crystalline structure of granules.

Size:

12-18 μm

Nucleus:

Round to oval; may have one flattened side

Nucleoli:

Usually not visible

Chromatin:

Coarse and more condensed than promyelocyte

Cytoplasm:

Colorless to pink

Granules:

Primary:

Few to moderate

Secondary:

Variable number; pale orange to dark orange; round; appear refractile

N/C RATIO:

2:1 to 1:1

Reference interval:

Bone marrow:

0% to 2%

Peripheral blood:

0%

Note:

This chapter begins with the image of the myelocyte, rather than the blast, because it is at the myelocyte stage that secondary granules, which define a cell as an eosinophil, first appear.

FIGURE 7–3 Eosinophilic sequence—eosinophilic metamyelocyte.

Eosinophilic metamyelocyte

FIGURE 7–4 Eosinophilic metamyelocyte.

Size:

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